To Investigate the Effect of Endometriosis on Intracytoplasmic Sperm Injection Outcome Among Infertile Women without Previous History of Ovarian Surgery
Objective: This study aimed to determine the impact of endometriosis on oocyte maturation in stimulated In-vitro Fertilization/Intra Cytoplasmic Sperm Injection (IVF/ICSI) outcomes. Study type, settings & duration: This retrospective study was conducted at Hameed Latif Hospital, Lahore from M...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Health Research Institute (HRI), National Institute of Health (NIH)
2025-04-01
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| Series: | Pakistan Journal of Medical Research |
| Subjects: | |
| Online Access: | https://www.pjmr.org.pk/index.php/pjmr/article/view/1081 |
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| Summary: | Objective: This study aimed to determine the impact of endometriosis on oocyte maturation in stimulated In-vitro Fertilization/Intra Cytoplasmic Sperm Injection (IVF/ICSI) outcomes.
Study type, settings & duration: This retrospective study was conducted at Hameed Latif Hospital, Lahore from March 2021 to March 2023.
Methodology: About 180 women were included in this study. All the study subjects were categorized into two groups in equal, where Group A presented with ovarian endometriosis and Group B presented women without endometriosis. Infertility parameters in both groups were same like age, body mass index (BMI), and infertility duration. Outcome parameters (ovarian reserve, fertilization rate, embryo quality, implantation rate and pregnancy outcomes) were compared in both groups.
Results: The mean age was 38 years in both groups. In group A, BMI and the Antral Follicle Count was lower as compared to group B. (p-value =0.04) The number of oocytes retrieved, matured, and fertilized was higher in group B (14±5.31, 13±4.60, 12.5±4.79) as compared to group A (5±2.52, 4.83±2.40, 3.66±1.03). All the variables were statistically significant with the p-value <0.05. The pregnancy rate in Group A was 30% and in Group B, it was 29%.
Conclusion: Oocyte number and quality are affected by endometriosis. However, ovarian endometrioma does not affect the embryo quality and the outcome of pregnancy.
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| ISSN: | 0030-9842 |