Linking genetic and phenotypic bedaquiline resistance in Mycobacterium tuberculosis strains from Georgia.

Linking genetic and phenotypic bedaquiline resistance in Mycobacterium tuberculosis strains from Georgia.

<h4>Introduction</h4>Resistance to bedaquiline - a novel, promising medication against tuberculosis (TB), is already emerging, and uncertainties regarding the role of the different resistance-conferring mutations complicate the development of molecular diagnostic tools for detecting resi...

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Main Authors: Nino Maghradze, Chloé Loiseau, Galo Adrian Goig, Nino Bablishvili, Levan Jugheli, Sonia Borrell, Nestani Tukvadze, Russell Ryan Kempker, Zaza Avaliani, Sebastien Gagneux
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0326794
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