Oxidative stress biomarkers as novel screening tools for trisomy 21: a case-control study

Oxidative stress biomarkers as novel screening tools for trisomy 21: a case-control study

Abstract Objective Oxidative stress plays a pivotal role in the pathogenesis of Down syndrome (Trisomy 21), as chromosome 21 harbors multiple genes involved in redox homeostasis and antioxidant defense mechanisms. This study aimed to evaluate the roles of transcription factors nuclear factor erythro...

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Bibliographic Details
Main Authors: Sinem Tekin, Aydin Ocal, Filiz Yarsilikal Guleroglu, Emine Ufuk Büyükkaya Ocal, Mervenur Al, Cagseli Göksu Ozgün Selcuk, Ali Cetin
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Pregnancy and Childbirth
Subjects:
Prenatal diagnosis
Transcription factors
Antioxidant enzymes
Down syndrome
Amniocentesis
Oxidative stress markers
Online Access:https://doi.org/10.1186/s12884-025-07601-4
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