AB0 Hemolytic Disease of the Newborn Development in the Child with АВ (IV) Blood Group from the Mother with 0 (I) Blood Group: Clinical Case

Background. Hemolytic disease of the newborn due to AB0 incompatibility typically develops when mother has 0 (I) blood group and prenatal child has А (II) or B (III). Mother’s antibodies аand рhave immune interaction with the child’s antigens A or B in such situation. It became possible for woman wi...

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Main Authors: Natalya L. Prokoptseva, Elena G. Neiman, Natalia A. Ilyenkova, Natalia Yu. Grishkevich
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2020-04-01
Series:Вопросы современной педиатрии
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Online Access:https://vsp.spr-journal.ru/jour/article/view/2304
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author Natalya L. Prokoptseva
Elena G. Neiman
Natalia A. Ilyenkova
Natalia Yu. Grishkevich
author_facet Natalya L. Prokoptseva
Elena G. Neiman
Natalia A. Ilyenkova
Natalia Yu. Grishkevich
author_sort Natalya L. Prokoptseva
collection DOAJ
description Background. Hemolytic disease of the newborn due to AB0 incompatibility typically develops when mother has 0 (I) blood group and prenatal child has А (II) or B (III). Mother’s antibodies аand рhave immune interaction with the child’s antigens A or B in such situation. It became possible for woman with 0 (I) group to carry of the child with AB (IV) group due to the use of donor ovum for in vitro fertilization. Naturally it is impossible. Clinical Case Description. Hemolytic disease of the newborn development in the child with АВ(IV) Blood Group from the Mother with 0 (I) Blood Group is demonstrated. It was the child of the second pregnancy resulting from in vitro fertilization of donor ovum with intracytoplasmic sperm injection and further tubal embryo transfer. The disease was manifested with icteric and anemia syndromes. Hyperbilirubinemia presented from birth, maximum level was on the 5th day of life. The treatment included phototherapy and immunoglobulin intravenous injections. The child's condition was stabilized by the 6th day. Conclusion. The hemolytic disease of the newborn development is possible when the woman with 0 (I) blood group is carrying the fetus with AB (IV) group especially when we are using donor ovum for in vitro fertilization without taking into account the blood group of the donor. It must be considered during preimplantation genetic testing, selection and tubal embryo transfer.
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publisher "Paediatrician" Publishers LLC
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series Вопросы современной педиатрии
spelling doaj-art-a330daedcee84392bb559ddfe2241fb92025-08-20T03:01:18Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352020-04-01191353910.15690/vsp.v19i1.20831865AB0 Hemolytic Disease of the Newborn Development in the Child with АВ (IV) Blood Group from the Mother with 0 (I) Blood Group: Clinical CaseNatalya L. Prokoptseva0Elena G. Neiman1Natalia A. Ilyenkova2Natalia Yu. Grishkevich3Krasnoyarsk State Medical University n. a. prof. V.F. Voino-YasenetskyKrasnoyarsk State Medical University n. a. prof. V.F. Voino-YasenetskyKrasnoyarsk State Medical University n. a. prof. V.F. Voino-YasenetskyKrasnoyarsk State Medical University n. a. prof. V.F. Voino-YasenetskyBackground. Hemolytic disease of the newborn due to AB0 incompatibility typically develops when mother has 0 (I) blood group and prenatal child has А (II) or B (III). Mother’s antibodies аand рhave immune interaction with the child’s antigens A or B in such situation. It became possible for woman with 0 (I) group to carry of the child with AB (IV) group due to the use of donor ovum for in vitro fertilization. Naturally it is impossible. Clinical Case Description. Hemolytic disease of the newborn development in the child with АВ(IV) Blood Group from the Mother with 0 (I) Blood Group is demonstrated. It was the child of the second pregnancy resulting from in vitro fertilization of donor ovum with intracytoplasmic sperm injection and further tubal embryo transfer. The disease was manifested with icteric and anemia syndromes. Hyperbilirubinemia presented from birth, maximum level was on the 5th day of life. The treatment included phototherapy and immunoglobulin intravenous injections. The child's condition was stabilized by the 6th day. Conclusion. The hemolytic disease of the newborn development is possible when the woman with 0 (I) blood group is carrying the fetus with AB (IV) group especially when we are using donor ovum for in vitro fertilization without taking into account the blood group of the donor. It must be considered during preimplantation genetic testing, selection and tubal embryo transfer.https://vsp.spr-journal.ru/jour/article/view/2304hemolytic disease of the newbornabo incompatibilityreproductive technologiesdonor ovumin vitro fertilization
spellingShingle Natalya L. Prokoptseva
Elena G. Neiman
Natalia A. Ilyenkova
Natalia Yu. Grishkevich
AB0 Hemolytic Disease of the Newborn Development in the Child with АВ (IV) Blood Group from the Mother with 0 (I) Blood Group: Clinical Case
Вопросы современной педиатрии
hemolytic disease of the newborn
abo incompatibility
reproductive technologies
donor ovum
in vitro fertilization
title AB0 Hemolytic Disease of the Newborn Development in the Child with АВ (IV) Blood Group from the Mother with 0 (I) Blood Group: Clinical Case
title_full AB0 Hemolytic Disease of the Newborn Development in the Child with АВ (IV) Blood Group from the Mother with 0 (I) Blood Group: Clinical Case
title_fullStr AB0 Hemolytic Disease of the Newborn Development in the Child with АВ (IV) Blood Group from the Mother with 0 (I) Blood Group: Clinical Case
title_full_unstemmed AB0 Hemolytic Disease of the Newborn Development in the Child with АВ (IV) Blood Group from the Mother with 0 (I) Blood Group: Clinical Case
title_short AB0 Hemolytic Disease of the Newborn Development in the Child with АВ (IV) Blood Group from the Mother with 0 (I) Blood Group: Clinical Case
title_sort ab0 hemolytic disease of the newborn development in the child with ав iv blood group from the mother with 0 i blood group clinical case
topic hemolytic disease of the newborn
abo incompatibility
reproductive technologies
donor ovum
in vitro fertilization
url https://vsp.spr-journal.ru/jour/article/view/2304
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