REM sleep quality is associated with balanced tonic activity of the locus coeruleus during wakefulness

REM sleep quality is associated with balanced tonic activity of the locus coeruleus during wakefulness

Abstract Background Animal studies established that the locus coeruleus (LC) plays important roles in sleep and wakefulness regulation. Whether it contributes to sleep variability in humans is not yet established. Here, we investigated if the in vivo activity of the LC is related to the variability...

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Main Authors: Nasrin Mortazavi, Puneet Talwar, Ekaterina Koshmanova, Roya Sharifpour, Elise Beckers, Alexandre Berger, Islay Campbell, Ilenia Paparella, Fermin Balda, Ismael Dardour Hamzaoui, Christian Berthomier, Christine Bastin, Christophe Phillips, Pierre Maquet, Fabienne Collette, Mikhail Zubkov, Laurent Lamalle, Gilles Vandewalle
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Journal of Biomedical Science
Subjects:
Locus coeruleus
Sleep
7 Tesla functional magnetic resonance imaging
Aging
Online Access:https://doi.org/10.1186/s12929-025-01127-9
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