Association between Self-Reported Habitual Snoring and Diabetes Mellitus: A Systemic Review and Meta-Analysis

Aim. Several studies have reported an association between self-reported habitual snoring and diabetes mellitus (DM); however, the results are inconsistent. Methods. Electronic databases including PubMed and EMBASE were searched. Odds ratios (ORs) and 95% confidence intervals (CIs) were used to asses...

Full description

Saved in:
Bibliographic Details
Main Authors: Xiaolu Xiong, Anyuan Zhong, Huajun Xu, Chun Wang
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2016/1958981
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850170234136166400
author Xiaolu Xiong
Anyuan Zhong
Huajun Xu
Chun Wang
author_facet Xiaolu Xiong
Anyuan Zhong
Huajun Xu
Chun Wang
author_sort Xiaolu Xiong
collection DOAJ
description Aim. Several studies have reported an association between self-reported habitual snoring and diabetes mellitus (DM); however, the results are inconsistent. Methods. Electronic databases including PubMed and EMBASE were searched. Odds ratios (ORs) and 95% confidence intervals (CIs) were used to assess the strength of the association between snoring and DM using a random-effects model. Heterogeneity, subgroup, and sensitivity analyses were also evaluated. Begg’s, Egger’s tests and funnel plots were used to evaluate publication bias. Results. A total of eight studies (six cross sectional and two prospective cohort studies) pooling 101,246 participants were included. Of the six cross sectional studies, the summary OR and 95% CI of DM in individuals that snore compared with nonsnorers were 1.37 (95% CI: 1.20–1.57, p<0.001). There was no heterogeneity across the included studies (I2=2.9%, p=0.408). When stratified by gender, the pooled OR (95% CI) was 1.59 (1.20–2.11) in females (n=12298), and 0.89 (0.65–1.22) in males (n=4276). Of the two prospective studies, the pooled RR was 1.65 (95% CI, 1.30–2.08). Conclusions. Self-reported habitual snoring is statistically associated with DM in females, but not in males. This meta-analysis indicates a need to paying attention to the effect of snoring on the occurrence of DM in females.
format Article
id doaj-art-a32cce50bec14b01a3fda80095a7c18a
institution OA Journals
issn 2314-6745
2314-6753
language English
publishDate 2016-01-01
publisher Wiley
record_format Article
series Journal of Diabetes Research
spelling doaj-art-a32cce50bec14b01a3fda80095a7c18a2025-08-20T02:20:32ZengWileyJournal of Diabetes Research2314-67452314-67532016-01-01201610.1155/2016/19589811958981Association between Self-Reported Habitual Snoring and Diabetes Mellitus: A Systemic Review and Meta-AnalysisXiaolu Xiong0Anyuan Zhong1Huajun Xu2Chun Wang3Department of Endocrinology, Drum Tower Clinical Medical College of Nanjing Medical University, 53 North Zhongshan Road, Nanjing 210008, ChinaDepartment of Respiratory Diseases, The Second Affiliated Hospital of Soochow University, 1055 Sanxiang Road, Suzhou 215004, ChinaDepartment of Otolaryngology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Otolaryngology Institute of Shanghai Jiao Tong University, 600 Yishan Road, Shanghai 200233, ChinaDepartment of Geriatrics, Drum Tower Clinical Medical College of Nanjing Medical University, 53 North Zhongshan Road, Nanjing 210008, ChinaAim. Several studies have reported an association between self-reported habitual snoring and diabetes mellitus (DM); however, the results are inconsistent. Methods. Electronic databases including PubMed and EMBASE were searched. Odds ratios (ORs) and 95% confidence intervals (CIs) were used to assess the strength of the association between snoring and DM using a random-effects model. Heterogeneity, subgroup, and sensitivity analyses were also evaluated. Begg’s, Egger’s tests and funnel plots were used to evaluate publication bias. Results. A total of eight studies (six cross sectional and two prospective cohort studies) pooling 101,246 participants were included. Of the six cross sectional studies, the summary OR and 95% CI of DM in individuals that snore compared with nonsnorers were 1.37 (95% CI: 1.20–1.57, p<0.001). There was no heterogeneity across the included studies (I2=2.9%, p=0.408). When stratified by gender, the pooled OR (95% CI) was 1.59 (1.20–2.11) in females (n=12298), and 0.89 (0.65–1.22) in males (n=4276). Of the two prospective studies, the pooled RR was 1.65 (95% CI, 1.30–2.08). Conclusions. Self-reported habitual snoring is statistically associated with DM in females, but not in males. This meta-analysis indicates a need to paying attention to the effect of snoring on the occurrence of DM in females.http://dx.doi.org/10.1155/2016/1958981
spellingShingle Xiaolu Xiong
Anyuan Zhong
Huajun Xu
Chun Wang
Association between Self-Reported Habitual Snoring and Diabetes Mellitus: A Systemic Review and Meta-Analysis
Journal of Diabetes Research
title Association between Self-Reported Habitual Snoring and Diabetes Mellitus: A Systemic Review and Meta-Analysis
title_full Association between Self-Reported Habitual Snoring and Diabetes Mellitus: A Systemic Review and Meta-Analysis
title_fullStr Association between Self-Reported Habitual Snoring and Diabetes Mellitus: A Systemic Review and Meta-Analysis
title_full_unstemmed Association between Self-Reported Habitual Snoring and Diabetes Mellitus: A Systemic Review and Meta-Analysis
title_short Association between Self-Reported Habitual Snoring and Diabetes Mellitus: A Systemic Review and Meta-Analysis
title_sort association between self reported habitual snoring and diabetes mellitus a systemic review and meta analysis
url http://dx.doi.org/10.1155/2016/1958981
work_keys_str_mv AT xiaoluxiong associationbetweenselfreportedhabitualsnoringanddiabetesmellitusasystemicreviewandmetaanalysis
AT anyuanzhong associationbetweenselfreportedhabitualsnoringanddiabetesmellitusasystemicreviewandmetaanalysis
AT huajunxu associationbetweenselfreportedhabitualsnoringanddiabetesmellitusasystemicreviewandmetaanalysis
AT chunwang associationbetweenselfreportedhabitualsnoringanddiabetesmellitusasystemicreviewandmetaanalysis