Trimodality therapy with salvage focal brachytherapy for seminal vesicle recurrence after prostate cancer brachytherapy

Salvage therapy is effective for treating local recurrence following radiation therapy for prostate cancer. Although surgery, radiation therapy, and hormonal therapy can be considered as options for salvage therapy for seminal vesicle recurrence of prostate cancer, there are reports of poor outcomes...

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Main Authors: Makoto Nakiri, Hirofumi Kurose, Shinnosuke Komine, Hiroki Suekane, Katsuaki Chikui, Kosuke Ueda, Keiichiro Uemura, Kiyoaki Nishihara, Koichiro Muraki, Chikayuki Hattori, Etsuyo Ogo, Tsukasa Igawa
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Urology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2214442025001688
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author Makoto Nakiri
Hirofumi Kurose
Shinnosuke Komine
Hiroki Suekane
Katsuaki Chikui
Kosuke Ueda
Keiichiro Uemura
Kiyoaki Nishihara
Koichiro Muraki
Chikayuki Hattori
Etsuyo Ogo
Tsukasa Igawa
author_facet Makoto Nakiri
Hirofumi Kurose
Shinnosuke Komine
Hiroki Suekane
Katsuaki Chikui
Kosuke Ueda
Keiichiro Uemura
Kiyoaki Nishihara
Koichiro Muraki
Chikayuki Hattori
Etsuyo Ogo
Tsukasa Igawa
author_sort Makoto Nakiri
collection DOAJ
description Salvage therapy is effective for treating local recurrence following radiation therapy for prostate cancer. Although surgery, radiation therapy, and hormonal therapy can be considered as options for salvage therapy for seminal vesicle recurrence of prostate cancer, there are reports of poor outcomes, and many cases involve treatment difficulties and post-treatment recurrence. In this article, we report our findings on the use of trimodality therapy, consisting of salvage focal brachytherapy, intensity-modulated radiation therapy, and hormonal therapy, in a patient who showed seminal vesicle recurrence 10 years after brachytherapy, with no major adverse events and no biochemical recurrence over 5 years.
format Article
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institution DOAJ
issn 2214-4420
language English
publishDate 2025-07-01
publisher Elsevier
record_format Article
series Urology Case Reports
spelling doaj-art-a3255b57b66f45699ecb6e4a35542fcd2025-08-20T02:48:07ZengElsevierUrology Case Reports2214-44202025-07-016110309710.1016/j.eucr.2025.103097Trimodality therapy with salvage focal brachytherapy for seminal vesicle recurrence after prostate cancer brachytherapyMakoto Nakiri0Hirofumi Kurose1Shinnosuke Komine2Hiroki Suekane3Katsuaki Chikui4Kosuke Ueda5Keiichiro Uemura6Kiyoaki Nishihara7Koichiro Muraki8Chikayuki Hattori9Etsuyo Ogo10Tsukasa Igawa11Department of Urology, Kurume University School of Medicine, Kurume, Japan; Corresponding author. author.Department of Urology, Kurume University School of Medicine, 67 Asahi-machi, Kurume, 830-0011, Japan.Department of Urology, Kurume University School of Medicine, Kurume, JapanDepartment of Urology, Kurume University School of Medicine, Kurume, JapanDepartment of Urology, Kurume University School of Medicine, Kurume, JapanDepartment of Urology, Kurume University School of Medicine, Kurume, JapanDepartment of Urology, Kurume University School of Medicine, Kurume, JapanDepartment of Urology, Kurume University School of Medicine, Kurume, JapanDepartment of Urology, Kurume University School of Medicine, Kurume, JapanDepartment of Radiology, Kurume University School of Medicine, Kurume, JapanDepartment of Radiology, Kurume University School of Medicine, Kurume, JapanDepartment of Radiology, Kurume University School of Medicine, Kurume, JapanDepartment of Urology, Kurume University School of Medicine, Kurume, JapanSalvage therapy is effective for treating local recurrence following radiation therapy for prostate cancer. Although surgery, radiation therapy, and hormonal therapy can be considered as options for salvage therapy for seminal vesicle recurrence of prostate cancer, there are reports of poor outcomes, and many cases involve treatment difficulties and post-treatment recurrence. In this article, we report our findings on the use of trimodality therapy, consisting of salvage focal brachytherapy, intensity-modulated radiation therapy, and hormonal therapy, in a patient who showed seminal vesicle recurrence 10 years after brachytherapy, with no major adverse events and no biochemical recurrence over 5 years.http://www.sciencedirect.com/science/article/pii/S2214442025001688Prostate cancerSalvage therapyBrachytherapySalvage focal brachytherapySeminal vesicle recurrence
spellingShingle Makoto Nakiri
Hirofumi Kurose
Shinnosuke Komine
Hiroki Suekane
Katsuaki Chikui
Kosuke Ueda
Keiichiro Uemura
Kiyoaki Nishihara
Koichiro Muraki
Chikayuki Hattori
Etsuyo Ogo
Tsukasa Igawa
Trimodality therapy with salvage focal brachytherapy for seminal vesicle recurrence after prostate cancer brachytherapy
Urology Case Reports
Prostate cancer
Salvage therapy
Brachytherapy
Salvage focal brachytherapy
Seminal vesicle recurrence
title Trimodality therapy with salvage focal brachytherapy for seminal vesicle recurrence after prostate cancer brachytherapy
title_full Trimodality therapy with salvage focal brachytherapy for seminal vesicle recurrence after prostate cancer brachytherapy
title_fullStr Trimodality therapy with salvage focal brachytherapy for seminal vesicle recurrence after prostate cancer brachytherapy
title_full_unstemmed Trimodality therapy with salvage focal brachytherapy for seminal vesicle recurrence after prostate cancer brachytherapy
title_short Trimodality therapy with salvage focal brachytherapy for seminal vesicle recurrence after prostate cancer brachytherapy
title_sort trimodality therapy with salvage focal brachytherapy for seminal vesicle recurrence after prostate cancer brachytherapy
topic Prostate cancer
Salvage therapy
Brachytherapy
Salvage focal brachytherapy
Seminal vesicle recurrence
url http://www.sciencedirect.com/science/article/pii/S2214442025001688
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