Efficacy of ultrasonography and mammography in detecting features of breast cancer
Introduction: Breast cancer (BC) is considered one of the most commonly diagnosed cancers. Early detection is critical for effective management. This study aims to assess the utility of ultrasonography (US) and mammography (MG) in detecting BC features. Methods: This retrospective cross-sectional st...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-01-01
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| Series: | Journal of Family Medicine and Primary Care |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jfmpc.jfmpc_1225_24 |
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| author | Sultan Abdulwadoud Alshoabi Amal A. Alareqi Moawia Gameraddin Awadia Gareeballah Kamal D. Alsultan Amel F. Alzain |
| author_facet | Sultan Abdulwadoud Alshoabi Amal A. Alareqi Moawia Gameraddin Awadia Gareeballah Kamal D. Alsultan Amel F. Alzain |
| author_sort | Sultan Abdulwadoud Alshoabi |
| collection | DOAJ |
| description | Introduction:
Breast cancer (BC) is considered one of the most commonly diagnosed cancers. Early detection is critical for effective management. This study aims to assess the utility of ultrasonography (US) and mammography (MG) in detecting BC features.
Methods:
This retrospective cross-sectional study involved the electronic records of 263 female patients diagnosed with BC. The mean age was 45.71 ± 12.25 years (17–90 years). A cross-tabulation test was performed to correlate the presence of each malignant feature (Yes/No) on both US and MG and the final ultrasonography diagnosis (benign/malignant). The compatibility between the presence of each feature on both imaging techniques was measured by the percentage of agreement in reporting the feature that was reported as Kappa. The sensitivity and specificity for each feature were calculated, and the receiver operating characteristic curve was used to measure the area under the curve for each feature on both modalities.
Results:
The strong compatibility between the two techniques was 87.1%, 94.29%, 66.92%, 79.85%, 77.56%, 77.18, and 79.84% for irregular shape, uncircumscribed, spiculated margins, tissue distortion, nipple retraction, skin thickening, and the presence of lymphadenopathy, respectively (P < 0.001). Boxplots show that the sensitivity of the US ranged from 37% to 95%, and the specificity ranged from 27% to 91%. However, MG’s sensitivity ranged from 44% to 93%, and the specificity ranged from 36% to 73%.
Conclusion:
US and MG images show similar morphological changes, enhancing diagnostic accuracy in breast lesions. US characterizes echogenicity, provides real-time imaging, and uses color and pulsed Doppler techniques for vascularity and lymphadenopathy detection, while MG is better for identifying different calcification types. |
| format | Article |
| id | doaj-art-a30d684648de4153b40d6ff4b7818132 |
| institution | Kabale University |
| issn | 2249-4863 2278-7135 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Family Medicine and Primary Care |
| spelling | doaj-art-a30d684648de4153b40d6ff4b78181322025-02-11T13:55:09ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632278-71352025-01-0114134134710.4103/jfmpc.jfmpc_1225_24Efficacy of ultrasonography and mammography in detecting features of breast cancerSultan Abdulwadoud AlshoabiAmal A. AlareqiMoawia GameraddinAwadia GareeballahKamal D. AlsultanAmel F. AlzainIntroduction: Breast cancer (BC) is considered one of the most commonly diagnosed cancers. Early detection is critical for effective management. This study aims to assess the utility of ultrasonography (US) and mammography (MG) in detecting BC features. Methods: This retrospective cross-sectional study involved the electronic records of 263 female patients diagnosed with BC. The mean age was 45.71 ± 12.25 years (17–90 years). A cross-tabulation test was performed to correlate the presence of each malignant feature (Yes/No) on both US and MG and the final ultrasonography diagnosis (benign/malignant). The compatibility between the presence of each feature on both imaging techniques was measured by the percentage of agreement in reporting the feature that was reported as Kappa. The sensitivity and specificity for each feature were calculated, and the receiver operating characteristic curve was used to measure the area under the curve for each feature on both modalities. Results: The strong compatibility between the two techniques was 87.1%, 94.29%, 66.92%, 79.85%, 77.56%, 77.18, and 79.84% for irregular shape, uncircumscribed, spiculated margins, tissue distortion, nipple retraction, skin thickening, and the presence of lymphadenopathy, respectively (P < 0.001). Boxplots show that the sensitivity of the US ranged from 37% to 95%, and the specificity ranged from 27% to 91%. However, MG’s sensitivity ranged from 44% to 93%, and the specificity ranged from 36% to 73%. Conclusion: US and MG images show similar morphological changes, enhancing diagnostic accuracy in breast lesions. US characterizes echogenicity, provides real-time imaging, and uses color and pulsed Doppler techniques for vascularity and lymphadenopathy detection, while MG is better for identifying different calcification types.https://journals.lww.com/10.4103/jfmpc.jfmpc_1225_24breast cancerirregular shape of breast lesionmammographyspiculated margins of breast lesionultrasonography |
| spellingShingle | Sultan Abdulwadoud Alshoabi Amal A. Alareqi Moawia Gameraddin Awadia Gareeballah Kamal D. Alsultan Amel F. Alzain Efficacy of ultrasonography and mammography in detecting features of breast cancer Journal of Family Medicine and Primary Care breast cancer irregular shape of breast lesion mammography spiculated margins of breast lesion ultrasonography |
| title | Efficacy of ultrasonography and mammography in detecting features of breast cancer |
| title_full | Efficacy of ultrasonography and mammography in detecting features of breast cancer |
| title_fullStr | Efficacy of ultrasonography and mammography in detecting features of breast cancer |
| title_full_unstemmed | Efficacy of ultrasonography and mammography in detecting features of breast cancer |
| title_short | Efficacy of ultrasonography and mammography in detecting features of breast cancer |
| title_sort | efficacy of ultrasonography and mammography in detecting features of breast cancer |
| topic | breast cancer irregular shape of breast lesion mammography spiculated margins of breast lesion ultrasonography |
| url | https://journals.lww.com/10.4103/jfmpc.jfmpc_1225_24 |
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