Physicochemical Properties and Cellular Responses of Strontium-Doped Gypsum Biomaterials
This paper describes some physical, structural, and biological properties of gypsum bioceramics doped with various amounts of strontium ions (0.19–2.23 wt%) and compares these properties with those of a pure gypsum as control. Strontium-doped gypsum (gypsum:Sr) was obtained by mixing calcium sulfate...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Bioinorganic Chemistry and Applications |
| Online Access: | http://dx.doi.org/10.1155/2012/976495 |
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| author | Amir Pouria Hadis Bandegani Milad Pourbaghi-Masouleh Saeed Hesaraki Masoud Alizadeh |
| author_facet | Amir Pouria Hadis Bandegani Milad Pourbaghi-Masouleh Saeed Hesaraki Masoud Alizadeh |
| author_sort | Amir Pouria |
| collection | DOAJ |
| description | This paper describes some physical, structural, and biological properties of gypsum bioceramics doped with various amounts of strontium ions (0.19–2.23 wt%) and compares these properties with those of a pure gypsum as control. Strontium-doped gypsum (gypsum:Sr) was obtained by mixing calcium sulfate hemihydrate powder and solutions of strontium nitrate followed by washing the specimens with distilled water to remove residual salts. Gypsum was the only phase found in the composition of both pure and gypsum:Sr, meanwhile a shift into lower diffraction angles was observed in the X-ray diffraction patterns of doped specimens. Microstructure of all gypsum specimens consisted of many rod-like small crystals entangled to each other with more elongation and higher thickness in the case of gypsum:Sr. The Sr-doped sample exhibited higher compressive strength and lower solubility than pure gypsum. A continuous release of strontium ions was observed from the gypsum:Sr during soaking it in simulated body fluid for 14 days. Compared to pure gypsum, the osteoblasts cultured on strontium-doped samples showed better proliferation rate and higher alkaline phosphatase activity, depending on Sr concentration. These observations can predict better in vivo behavior of strontium-doped gypsum compared to pure one. |
| format | Article |
| id | doaj-art-a2fefb14fe03494dabbbff0ee9a23f97 |
| institution | OA Journals |
| issn | 1565-3633 1687-479X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Bioinorganic Chemistry and Applications |
| spelling | doaj-art-a2fefb14fe03494dabbbff0ee9a23f972025-08-20T02:20:30ZengWileyBioinorganic Chemistry and Applications1565-36331687-479X2012-01-01201210.1155/2012/976495976495Physicochemical Properties and Cellular Responses of Strontium-Doped Gypsum BiomaterialsAmir Pouria0Hadis Bandegani1Milad Pourbaghi-Masouleh2Saeed Hesaraki3Masoud Alizadeh4Nanotechnology and Advanced Materials Department, Materials and Energy Research Center, P.O. Box 31787/316, Karaj 3177983634, IranNanotechnology and Advanced Materials Department, Materials and Energy Research Center, P.O. Box 31787/316, Karaj 3177983634, IranNanotechnology and Advanced Materials Department, Materials and Energy Research Center, P.O. Box 31787/316, Karaj 3177983634, IranNanotechnology and Advanced Materials Department, Materials and Energy Research Center, P.O. Box 31787/316, Karaj 3177983634, IranCeramics Department, Materials and Energy Reserach Center, P.O. Box 31787/316, Karaj 3177983634, IranThis paper describes some physical, structural, and biological properties of gypsum bioceramics doped with various amounts of strontium ions (0.19–2.23 wt%) and compares these properties with those of a pure gypsum as control. Strontium-doped gypsum (gypsum:Sr) was obtained by mixing calcium sulfate hemihydrate powder and solutions of strontium nitrate followed by washing the specimens with distilled water to remove residual salts. Gypsum was the only phase found in the composition of both pure and gypsum:Sr, meanwhile a shift into lower diffraction angles was observed in the X-ray diffraction patterns of doped specimens. Microstructure of all gypsum specimens consisted of many rod-like small crystals entangled to each other with more elongation and higher thickness in the case of gypsum:Sr. The Sr-doped sample exhibited higher compressive strength and lower solubility than pure gypsum. A continuous release of strontium ions was observed from the gypsum:Sr during soaking it in simulated body fluid for 14 days. Compared to pure gypsum, the osteoblasts cultured on strontium-doped samples showed better proliferation rate and higher alkaline phosphatase activity, depending on Sr concentration. These observations can predict better in vivo behavior of strontium-doped gypsum compared to pure one.http://dx.doi.org/10.1155/2012/976495 |
| spellingShingle | Amir Pouria Hadis Bandegani Milad Pourbaghi-Masouleh Saeed Hesaraki Masoud Alizadeh Physicochemical Properties and Cellular Responses of Strontium-Doped Gypsum Biomaterials Bioinorganic Chemistry and Applications |
| title | Physicochemical Properties and Cellular Responses of Strontium-Doped Gypsum Biomaterials |
| title_full | Physicochemical Properties and Cellular Responses of Strontium-Doped Gypsum Biomaterials |
| title_fullStr | Physicochemical Properties and Cellular Responses of Strontium-Doped Gypsum Biomaterials |
| title_full_unstemmed | Physicochemical Properties and Cellular Responses of Strontium-Doped Gypsum Biomaterials |
| title_short | Physicochemical Properties and Cellular Responses of Strontium-Doped Gypsum Biomaterials |
| title_sort | physicochemical properties and cellular responses of strontium doped gypsum biomaterials |
| url | http://dx.doi.org/10.1155/2012/976495 |
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