Research on the diagnosis model of osteoarthritis based on methylation-related genes using machine learning algorithms

Research on the diagnosis model of osteoarthritis based on methylation-related genes using machine learning algorithms

ObjectiveTo construct a diagnostic model of osteoarthritis related to methylation genes using machine learning algorithms, and analyze its prognostic value and biological functions.MethodsThe GSE 63695 and GSE162484 datasets including human osteoarthritis (OA) and normal samples were downloaded from...

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Bibliographic Details
Main Authors: Xu Cui, Houlin Ji, Shengyang Guo, Ju Liu, Linyuan Zhang, Yongwei Jia, Yin Cui, Xiaoxiao Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Genetics
Subjects:
osteoarthritis
methylation
machine learning
diagnostic model
biological functions
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2025.1595676/full
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