Benzodiazepine and Opioid Withdrawal Induced Neuroleptic Malignant Like Syndrome: A Clinical Case Report With Management Complexities
ABSTRACT Delirium may be an uncommon side effect of withdrawal from benzodiazepines and opioids. A small number of case reports illustrate the catatonia and malignant catatonia linked to withdrawal from opioids and benzodiazepines. This case presentation showed the patient experienced symptoms simil...
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| Format: | Article |
| Language: | English |
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Wiley
2025-06-01
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| Series: | Neuropsychopharmacology Reports |
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| Online Access: | https://doi.org/10.1002/npr2.70020 |
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| author | Behnam Abbasi Forouzan Elyasi Fateme Heydari Roya Ghasemian |
| author_facet | Behnam Abbasi Forouzan Elyasi Fateme Heydari Roya Ghasemian |
| author_sort | Behnam Abbasi |
| collection | DOAJ |
| description | ABSTRACT Delirium may be an uncommon side effect of withdrawal from benzodiazepines and opioids. A small number of case reports illustrate the catatonia and malignant catatonia linked to withdrawal from opioids and benzodiazepines. This case presentation showed the patient experienced symptoms similar to Neuroleptic Malignant Syndrome after abruptly stopping high doses of opioids and alprazolam after prolonged usage. This patient was a 54‐year‐old man in a northern Iranian city with dependency on 20–30 mg of alprazolam and 120–150 mg of acetaminophen‐codeine daily for over a year and a half. The clinical difficulty of identifying and treating Neuroleptic Malignant Like Syndrome (NMLS), which is brought on by benzodiazepine and opioid withdrawal, is illustrated by this case. |
| format | Article |
| id | doaj-art-a2e4dc8156b0449f92dcfd49c7211ae7 |
| institution | OA Journals |
| issn | 2574-173X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neuropsychopharmacology Reports |
| spelling | doaj-art-a2e4dc8156b0449f92dcfd49c7211ae72025-08-20T02:20:55ZengWileyNeuropsychopharmacology Reports2574-173X2025-06-01452n/an/a10.1002/npr2.70020Benzodiazepine and Opioid Withdrawal Induced Neuroleptic Malignant Like Syndrome: A Clinical Case Report With Management ComplexitiesBehnam Abbasi0Forouzan Elyasi1Fateme Heydari2Roya Ghasemian3Department of Psychiatry Faculty of Medicine, Mazandaran University of Medical Sciences Sari IranDepartment of Psychiatry Faculty of Medicine, Mazandaran University of Medical Sciences Sari IranDepartment of Anesthesiology Faculty of Medicine, Mazandaran University of Medical Sciences Sari IranAntimicrobial Resistance Research Center, Department of Infectious Diseases Mazandaran University of Medical Sciences Sari IranABSTRACT Delirium may be an uncommon side effect of withdrawal from benzodiazepines and opioids. A small number of case reports illustrate the catatonia and malignant catatonia linked to withdrawal from opioids and benzodiazepines. This case presentation showed the patient experienced symptoms similar to Neuroleptic Malignant Syndrome after abruptly stopping high doses of opioids and alprazolam after prolonged usage. This patient was a 54‐year‐old man in a northern Iranian city with dependency on 20–30 mg of alprazolam and 120–150 mg of acetaminophen‐codeine daily for over a year and a half. The clinical difficulty of identifying and treating Neuroleptic Malignant Like Syndrome (NMLS), which is brought on by benzodiazepine and opioid withdrawal, is illustrated by this case.https://doi.org/10.1002/npr2.70020benzodiazepinecodeineneuroleptic malignantwithdrawal |
| spellingShingle | Behnam Abbasi Forouzan Elyasi Fateme Heydari Roya Ghasemian Benzodiazepine and Opioid Withdrawal Induced Neuroleptic Malignant Like Syndrome: A Clinical Case Report With Management Complexities Neuropsychopharmacology Reports benzodiazepine codeine neuroleptic malignant withdrawal |
| title | Benzodiazepine and Opioid Withdrawal Induced Neuroleptic Malignant Like Syndrome: A Clinical Case Report With Management Complexities |
| title_full | Benzodiazepine and Opioid Withdrawal Induced Neuroleptic Malignant Like Syndrome: A Clinical Case Report With Management Complexities |
| title_fullStr | Benzodiazepine and Opioid Withdrawal Induced Neuroleptic Malignant Like Syndrome: A Clinical Case Report With Management Complexities |
| title_full_unstemmed | Benzodiazepine and Opioid Withdrawal Induced Neuroleptic Malignant Like Syndrome: A Clinical Case Report With Management Complexities |
| title_short | Benzodiazepine and Opioid Withdrawal Induced Neuroleptic Malignant Like Syndrome: A Clinical Case Report With Management Complexities |
| title_sort | benzodiazepine and opioid withdrawal induced neuroleptic malignant like syndrome a clinical case report with management complexities |
| topic | benzodiazepine codeine neuroleptic malignant withdrawal |
| url | https://doi.org/10.1002/npr2.70020 |
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