Polysaccharide as gelatin subtitute material in halal drug delivery system

Drug delivery system describe the journey of a drug to get the target of action. The material used in drug delivery is very diverse and according to the therapymethod. So far, the use of gelatin in the pharmaceutical is very extensive, such as material in the drug delivery system. Gelatin can be pro...

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Main Authors: Hayyun Durrotul Faridah, Tri Susanti
Format: Article
Language:English
Published: Universitas Airlangga 2018-12-01
Series:Journal of Halal Product and Research
Subjects:
Online Access:https://e-journal.unair.ac.id/JHPR/article/view/10507
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author Hayyun Durrotul Faridah
Tri Susanti
author_facet Hayyun Durrotul Faridah
Tri Susanti
author_sort Hayyun Durrotul Faridah
collection DOAJ
description Drug delivery system describe the journey of a drug to get the target of action. The material used in drug delivery is very diverse and according to the therapymethod. So far, the use of gelatin in the pharmaceutical is very extensive, such as material in the drug delivery system. Gelatin can be produced from the extraction of animal collagen like from skin, bone and connective tissue. They are usually taken from the products of animal slaughterhouse products such as pigs and cattles. To produce a halal material, starting from the selection of basic materials until production of a material must be appropiate with Islamic rules. Like the selection of basic materials that getting from halal animals, the slaughter process is according to Islamic law and does not contain alcohol or other non-halal ingredients. However, today the use of pig skin as a gelatin base material is preferred because of its abundant availability and ease of processing. But actually pigs are animals that should not be consumed in Islam. The large number of pharmaceutical products derivating from pigs is a problem for a Muslim because it can be non-halal product. Therefore it is necessary to look for alternative gelatin as drug delivery system. One of the alternative material that can be used is a polysaccharide which is a natural polymer with very abundant availability in nature. For example carrageenan which is a polysaccharide extracted from the red seaweed, alginate extracted from brown seaweed, and xanthan gum which is the excretion of Xanthomonas campestris bacteria. The polysaccharide can be used as a halal drug delivery system and has the potential to be developed further so that it has better quality than gelatin.
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spelling doaj-art-a2e4b39ce1324afea319b002ff6d99ec2025-08-20T02:49:32ZengUniversitas AirlanggaJournal of Halal Product and Research2654-94092654-97782018-12-0112152110.20473/jhpr.vol.1-issue.2.15-218338Polysaccharide as gelatin subtitute material in halal drug delivery systemHayyun Durrotul Faridah0Tri Susanti1Program Studi Biologi, Fakultas Sains dan Teknologi,Universitas Airlangga Jl. Mulyorejo, Surabaya 60115Program Studi Biologi, Fakultas Sains dan Teknologi,Universitas Airlangga Jl. Mulyorejo, Surabaya 60115Drug delivery system describe the journey of a drug to get the target of action. The material used in drug delivery is very diverse and according to the therapymethod. So far, the use of gelatin in the pharmaceutical is very extensive, such as material in the drug delivery system. Gelatin can be produced from the extraction of animal collagen like from skin, bone and connective tissue. They are usually taken from the products of animal slaughterhouse products such as pigs and cattles. To produce a halal material, starting from the selection of basic materials until production of a material must be appropiate with Islamic rules. Like the selection of basic materials that getting from halal animals, the slaughter process is according to Islamic law and does not contain alcohol or other non-halal ingredients. However, today the use of pig skin as a gelatin base material is preferred because of its abundant availability and ease of processing. But actually pigs are animals that should not be consumed in Islam. The large number of pharmaceutical products derivating from pigs is a problem for a Muslim because it can be non-halal product. Therefore it is necessary to look for alternative gelatin as drug delivery system. One of the alternative material that can be used is a polysaccharide which is a natural polymer with very abundant availability in nature. For example carrageenan which is a polysaccharide extracted from the red seaweed, alginate extracted from brown seaweed, and xanthan gum which is the excretion of Xanthomonas campestris bacteria. The polysaccharide can be used as a halal drug delivery system and has the potential to be developed further so that it has better quality than gelatin.https://e-journal.unair.ac.id/JHPR/article/view/10507halaldrug delivery systemgelatinepolysaccharide
spellingShingle Hayyun Durrotul Faridah
Tri Susanti
Polysaccharide as gelatin subtitute material in halal drug delivery system
Journal of Halal Product and Research
halal
drug delivery system
gelatine
polysaccharide
title Polysaccharide as gelatin subtitute material in halal drug delivery system
title_full Polysaccharide as gelatin subtitute material in halal drug delivery system
title_fullStr Polysaccharide as gelatin subtitute material in halal drug delivery system
title_full_unstemmed Polysaccharide as gelatin subtitute material in halal drug delivery system
title_short Polysaccharide as gelatin subtitute material in halal drug delivery system
title_sort polysaccharide as gelatin subtitute material in halal drug delivery system
topic halal
drug delivery system
gelatine
polysaccharide
url https://e-journal.unair.ac.id/JHPR/article/view/10507
work_keys_str_mv AT hayyundurrotulfaridah polysaccharideasgelatinsubtitutematerialinhalaldrugdeliverysystem
AT trisusanti polysaccharideasgelatinsubtitutematerialinhalaldrugdeliverysystem