Cardiotoxic and Cardioprotective Effects of Methylene Blue in the Animal Model of Cardiac Ischemia and Reperfusion

Cardiotoxic and Cardioprotective Effects of Methylene Blue in the Animal Model of Cardiac Ischemia and Reperfusion

<b>Background/Objectives:</b> Treatment of patients with myocardial ischemic diseases crucially involves cardiac reperfusion (CR). However, oxidative stress and tissue lesions caused by CR may also lead to lethal complications, such as arrythmias and vasoplegic syndrome (VS). Although me...

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Main Authors: Hezio Jadir Fernandes Junior, Erisvaldo Amarante de Araújo, José Antônio Machado Junior, Fabio Marinho Lutz Motta, Gabriela Ferrazzano Guarize, Lucas Chen Cheng, Junaid Tantray, Jand Venes Rolim Medeiros, Lucas Antonio Duarte Nicolau, Adriano Henrique Pereira Barbosa, Adriano Caixeta, Isadora S. Rocco, Solange Guizilini, Marcelo Pires-Oliveira, Murched Omar Taha, Afonso Caricati-Neto, Walter José Gomes, Fernando Sabia Tallo, Francisco Sandro Menezes-Rodrigues
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biomedicines
Subjects:
cardiac ischemia and reperfusion
myocardial injuries
cardiotoxicity
cardioprotection
arrhythmias
methylene blue
Online Access:https://www.mdpi.com/2227-9059/12/11/2575
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