Artificial Intelligence and Its Role in the Diagnosis and Prediction of Adverse Events in Acute Coronary Syndrome: A Narrative Review of the Literature

Acute coronary syndrome (ACS) is a global health concern that requires rapid and accurate diagnosis for timely intervention and better patient outcomes. With the emergence of Artificial Intelligence (AI), significant advancements have been made in improving diagnostic accuracy, efficiency, and risk...

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Main Authors: Andrea Mariani, Carmen Anna Maria Spaccarotella, Francesco Saverio Rea, Anna Franzone, Raffaele Piccolo, Domenico Simone Castiello, Ciro Indolfi, Giovanni Esposito
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Life
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Online Access:https://www.mdpi.com/2075-1729/15/4/515
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author Andrea Mariani
Carmen Anna Maria Spaccarotella
Francesco Saverio Rea
Anna Franzone
Raffaele Piccolo
Domenico Simone Castiello
Ciro Indolfi
Giovanni Esposito
author_facet Andrea Mariani
Carmen Anna Maria Spaccarotella
Francesco Saverio Rea
Anna Franzone
Raffaele Piccolo
Domenico Simone Castiello
Ciro Indolfi
Giovanni Esposito
author_sort Andrea Mariani
collection DOAJ
description Acute coronary syndrome (ACS) is a global health concern that requires rapid and accurate diagnosis for timely intervention and better patient outcomes. With the emergence of Artificial Intelligence (AI), significant advancements have been made in improving diagnostic accuracy, efficiency, and risk stratification in ACS management. This narrative review examines the current landscape of AI applications in ACS diagnosis and risk stratification, emphasizing key methodologies, technical and clinical implementation challenges, and also possible future research directions. Moreover, unlike previous reviews, this paper also focuses on ethical and legal issues and the feasibility of clinical applications.
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spelling doaj-art-a2e078597354477cb2aa3a1dc1866ce22025-08-20T02:18:09ZengMDPI AGLife2075-17292025-03-0115451510.3390/life15040515Artificial Intelligence and Its Role in the Diagnosis and Prediction of Adverse Events in Acute Coronary Syndrome: A Narrative Review of the LiteratureAndrea Mariani0Carmen Anna Maria Spaccarotella1Francesco Saverio Rea2Anna Franzone3Raffaele Piccolo4Domenico Simone Castiello5Ciro Indolfi6Giovanni Esposito7Department of Advanced Biomedical Sciences, University of Naples “Federico II”, Via Sergio Pansini 5, 80131 Naples, ItalyDepartment of Advanced Biomedical Sciences, University of Naples “Federico II”, Via Sergio Pansini 5, 80131 Naples, ItalyDepartment of Advanced Biomedical Sciences, University of Naples “Federico II”, Via Sergio Pansini 5, 80131 Naples, ItalyDepartment of Advanced Biomedical Sciences, University of Naples “Federico II”, Via Sergio Pansini 5, 80131 Naples, ItalyDepartment of Advanced Biomedical Sciences, University of Naples “Federico II”, Via Sergio Pansini 5, 80131 Naples, ItalyDepartment of Advanced Biomedical Sciences, University of Naples “Federico II”, Via Sergio Pansini 5, 80131 Naples, ItalyDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via Pietro Bucci, Arcavacata, 87036 Rende, CS, ItalyDepartment of Advanced Biomedical Sciences, University of Naples “Federico II”, Via Sergio Pansini 5, 80131 Naples, ItalyAcute coronary syndrome (ACS) is a global health concern that requires rapid and accurate diagnosis for timely intervention and better patient outcomes. With the emergence of Artificial Intelligence (AI), significant advancements have been made in improving diagnostic accuracy, efficiency, and risk stratification in ACS management. This narrative review examines the current landscape of AI applications in ACS diagnosis and risk stratification, emphasizing key methodologies, technical and clinical implementation challenges, and also possible future research directions. Moreover, unlike previous reviews, this paper also focuses on ethical and legal issues and the feasibility of clinical applications.https://www.mdpi.com/2075-1729/15/4/515artificial intelligenceacute coronary syndromenarrative reviewmachine learning
spellingShingle Andrea Mariani
Carmen Anna Maria Spaccarotella
Francesco Saverio Rea
Anna Franzone
Raffaele Piccolo
Domenico Simone Castiello
Ciro Indolfi
Giovanni Esposito
Artificial Intelligence and Its Role in the Diagnosis and Prediction of Adverse Events in Acute Coronary Syndrome: A Narrative Review of the Literature
Life
artificial intelligence
acute coronary syndrome
narrative review
machine learning
title Artificial Intelligence and Its Role in the Diagnosis and Prediction of Adverse Events in Acute Coronary Syndrome: A Narrative Review of the Literature
title_full Artificial Intelligence and Its Role in the Diagnosis and Prediction of Adverse Events in Acute Coronary Syndrome: A Narrative Review of the Literature
title_fullStr Artificial Intelligence and Its Role in the Diagnosis and Prediction of Adverse Events in Acute Coronary Syndrome: A Narrative Review of the Literature
title_full_unstemmed Artificial Intelligence and Its Role in the Diagnosis and Prediction of Adverse Events in Acute Coronary Syndrome: A Narrative Review of the Literature
title_short Artificial Intelligence and Its Role in the Diagnosis and Prediction of Adverse Events in Acute Coronary Syndrome: A Narrative Review of the Literature
title_sort artificial intelligence and its role in the diagnosis and prediction of adverse events in acute coronary syndrome a narrative review of the literature
topic artificial intelligence
acute coronary syndrome
narrative review
machine learning
url https://www.mdpi.com/2075-1729/15/4/515
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