Identification of Meibomian gland stem cell populations and mechanisms of aging

Identification of Meibomian gland stem cell populations and mechanisms of aging

Abstract Meibomian glands secrete lipid-rich meibum, which prevents tear evaporation. Aging-related Meibomian gland shrinkage may result in part from stem cell exhaustion and is associated with evaporative dry eye disease, a common condition lacking effective treatment. The identities and niche of M...

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Main Authors: Xuming Zhu, Mingang Xu, Celine Portal, Yvonne Lin, Alyssa Ferdinand, Tien Peng, Edward E. Morrisey, Andrzej A. Dlugosz, Joseph M. Castellano, Vivian Lee, John T. Seykora, Sunny Y. Wong, Carlo Iomini, Sarah E. Millar
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56907-6
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https://doi.org/10.1038/s41467-025-56907-6

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