UAE-HPLC-UV: New Contribution for Fast Determination of Total Isothiocyanates in Brassicaceae Vegetables

Total isothiocyanates content (ITC) is considered a good indicator of bioactive compounds responsible for beneficial effects related to Brassicaceae vegetables. Analytical performance is a critical factor for routine analysis in plant tissues. The extraction technique for isolating phytochemicals fr...

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Main Authors: Cecilia M. Fusari, Daniela A. Locatelli, Jorgelina C. Altamirano, Alejandra B. Camargo
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2015/294601
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author Cecilia M. Fusari
Daniela A. Locatelli
Jorgelina C. Altamirano
Alejandra B. Camargo
author_facet Cecilia M. Fusari
Daniela A. Locatelli
Jorgelina C. Altamirano
Alejandra B. Camargo
author_sort Cecilia M. Fusari
collection DOAJ
description Total isothiocyanates content (ITC) is considered a good indicator of bioactive compounds responsible for beneficial effects related to Brassicaceae vegetables. Analytical performance is a critical factor for routine analysis in plant tissues. The extraction technique for isolating phytochemicals from Brassicaceae vegetables is currently the bottleneck of the methodology. The aim of this work was to optimize this step in the analytical process. Fast and less expensive alternative, based on ultrasound-assisted extraction technique (UAE) for direct extraction of GLS into an aqueous phase and further analysis of the hydrolysis product, was optimized. Full factorial (2k) design followed by Central Composite Design (CCD) was used to obtain the optimum extraction conditions. Selected conditions were homogenization time (9 min); ultrasound bath time (5 min); and sample-to-solvent ratio (1 : 5 w/v mg mL−1). The proposed analytical methodology exhibits satisfactory analytical performance in terms of linearity, precision (RSD < 2.4%), and limits of detection (26 nmol g−1 w.w.). The new analytical methodology was applied to cauliflower, cabbage, watercress, and broccoli samples with recoveries higher than 86%. The UAE extraction technique was showed to be efficient for real samples analysis leading to sensible, selective, and reproducible methodology for ITC analysis.
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institution Kabale University
issn 2090-9063
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language English
publishDate 2015-01-01
publisher Wiley
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series Journal of Chemistry
spelling doaj-art-a2ca5a7a5f574935a0edd8bc233e7bbf2025-08-20T03:38:19ZengWileyJournal of Chemistry2090-90632090-90712015-01-01201510.1155/2015/294601294601UAE-HPLC-UV: New Contribution for Fast Determination of Total Isothiocyanates in Brassicaceae VegetablesCecilia M. Fusari0Daniela A. Locatelli1Jorgelina C. Altamirano2Alejandra B. Camargo3Instituto de Biología Agrícola de Mendoza (IBAM), CONICET, Almirante Brown 500, Chacras de Coria, 5505 Mendoza, ArgentinaInstituto de Biología Agrícola de Mendoza (IBAM), CONICET, Almirante Brown 500, Chacras de Coria, 5505 Mendoza, ArgentinaLaboratorio de Química Ambiental, Instituto Argentino de Nivología, Glaciología y Ciencias Ambientales (IANIGLA), CONICET, Avenida Ruiz Leal s/n, Parque General San Martín, 5500 Mendoza, ArgentinaInstituto de Biología Agrícola de Mendoza (IBAM), CONICET, Almirante Brown 500, Chacras de Coria, 5505 Mendoza, ArgentinaTotal isothiocyanates content (ITC) is considered a good indicator of bioactive compounds responsible for beneficial effects related to Brassicaceae vegetables. Analytical performance is a critical factor for routine analysis in plant tissues. The extraction technique for isolating phytochemicals from Brassicaceae vegetables is currently the bottleneck of the methodology. The aim of this work was to optimize this step in the analytical process. Fast and less expensive alternative, based on ultrasound-assisted extraction technique (UAE) for direct extraction of GLS into an aqueous phase and further analysis of the hydrolysis product, was optimized. Full factorial (2k) design followed by Central Composite Design (CCD) was used to obtain the optimum extraction conditions. Selected conditions were homogenization time (9 min); ultrasound bath time (5 min); and sample-to-solvent ratio (1 : 5 w/v mg mL−1). The proposed analytical methodology exhibits satisfactory analytical performance in terms of linearity, precision (RSD < 2.4%), and limits of detection (26 nmol g−1 w.w.). The new analytical methodology was applied to cauliflower, cabbage, watercress, and broccoli samples with recoveries higher than 86%. The UAE extraction technique was showed to be efficient for real samples analysis leading to sensible, selective, and reproducible methodology for ITC analysis.http://dx.doi.org/10.1155/2015/294601
spellingShingle Cecilia M. Fusari
Daniela A. Locatelli
Jorgelina C. Altamirano
Alejandra B. Camargo
UAE-HPLC-UV: New Contribution for Fast Determination of Total Isothiocyanates in Brassicaceae Vegetables
Journal of Chemistry
title UAE-HPLC-UV: New Contribution for Fast Determination of Total Isothiocyanates in Brassicaceae Vegetables
title_full UAE-HPLC-UV: New Contribution for Fast Determination of Total Isothiocyanates in Brassicaceae Vegetables
title_fullStr UAE-HPLC-UV: New Contribution for Fast Determination of Total Isothiocyanates in Brassicaceae Vegetables
title_full_unstemmed UAE-HPLC-UV: New Contribution for Fast Determination of Total Isothiocyanates in Brassicaceae Vegetables
title_short UAE-HPLC-UV: New Contribution for Fast Determination of Total Isothiocyanates in Brassicaceae Vegetables
title_sort uae hplc uv new contribution for fast determination of total isothiocyanates in brassicaceae vegetables
url http://dx.doi.org/10.1155/2015/294601
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