Do P2Y12 receptor inhibitors prescribed poststroke modify the risk of cognitive disorder or dementia? Protocol for a target trial using multiple national Swedish registries

Do P2Y12 receptor inhibitors prescribed poststroke modify the risk of cognitive disorder or dementia? Protocol for a target trial using multiple national Swedish registries

Introduction The target of a class of antiplatelet medicines, P2Y12R inhibitors, exists both on platelets and on brain immune cells (microglia). This protocol aims to describe a causal (based on a counterfactual model) approach for analysing whether P2Y12R inhibitors prescribed for secondary prevent...

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Main Authors: John Attia, Michael Nilsson, Frederick R Walker, Christopher Oldmeadow, Michael Pollack, Jenny Nyberg, Sara Gustavsson, N David Åberg, Georg Hans Kuhn, Madeleine Hinwood, Marina Ilicic, Chris Levi, Sarah J Johnson, Leeanne M Carey, Lucy Leigh, Neil Spratt, Thomas Lindén
Format: Article
Language:English
Published: BMJ Publishing Group 2022-05-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/12/5/e058244.full
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