Lung Segmentation in 4D CT Volumes Based on Robust Active Shape Model Matching

Dynamic and longitudinal lung CT imaging produce 4D lung image data sets, enabling applications like radiation treatment planning or assessment of response to treatment of lung diseases. In this paper, we present a 4D lung segmentation method that mutually utilizes all individual CT volumes to deriv...

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Main Authors: Gurman Gill, Reinhard R. Beichel
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:International Journal of Biomedical Imaging
Online Access:http://dx.doi.org/10.1155/2015/125648
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author Gurman Gill
Reinhard R. Beichel
author_facet Gurman Gill
Reinhard R. Beichel
author_sort Gurman Gill
collection DOAJ
description Dynamic and longitudinal lung CT imaging produce 4D lung image data sets, enabling applications like radiation treatment planning or assessment of response to treatment of lung diseases. In this paper, we present a 4D lung segmentation method that mutually utilizes all individual CT volumes to derive segmentations for each CT data set. Our approach is based on a 3D robust active shape model and extends it to fully utilize 4D lung image data sets. This yields an initial segmentation for the 4D volume, which is then refined by using a 4D optimal surface finding algorithm. The approach was evaluated on a diverse set of 152 CT scans of normal and diseased lungs, consisting of total lung capacity and functional residual capacity scan pairs. In addition, a comparison to a 3D segmentation method and a registration based 4D lung segmentation approach was performed. The proposed 4D method obtained an average Dice coefficient of 0.9773±0.0254, which was statistically significantly better (p value ≪0.001) than the 3D method (0.9659±0.0517). Compared to the registration based 4D method, our method obtained better or similar performance, but was 58.6% faster. Also, the method can be easily expanded to process 4D CT data sets consisting of several volumes.
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spelling doaj-art-a2ba9f89ed574ba2af62eea3e16b40f62025-02-03T01:02:25ZengWileyInternational Journal of Biomedical Imaging1687-41881687-41962015-01-01201510.1155/2015/125648125648Lung Segmentation in 4D CT Volumes Based on Robust Active Shape Model MatchingGurman Gill0Reinhard R. Beichel1Department of Electrical and Computer Engineering, The University of Iowa, Iowa City, IA 52242, USADepartment of Electrical and Computer Engineering, The University of Iowa, Iowa City, IA 52242, USADynamic and longitudinal lung CT imaging produce 4D lung image data sets, enabling applications like radiation treatment planning or assessment of response to treatment of lung diseases. In this paper, we present a 4D lung segmentation method that mutually utilizes all individual CT volumes to derive segmentations for each CT data set. Our approach is based on a 3D robust active shape model and extends it to fully utilize 4D lung image data sets. This yields an initial segmentation for the 4D volume, which is then refined by using a 4D optimal surface finding algorithm. The approach was evaluated on a diverse set of 152 CT scans of normal and diseased lungs, consisting of total lung capacity and functional residual capacity scan pairs. In addition, a comparison to a 3D segmentation method and a registration based 4D lung segmentation approach was performed. The proposed 4D method obtained an average Dice coefficient of 0.9773±0.0254, which was statistically significantly better (p value ≪0.001) than the 3D method (0.9659±0.0517). Compared to the registration based 4D method, our method obtained better or similar performance, but was 58.6% faster. Also, the method can be easily expanded to process 4D CT data sets consisting of several volumes.http://dx.doi.org/10.1155/2015/125648
spellingShingle Gurman Gill
Reinhard R. Beichel
Lung Segmentation in 4D CT Volumes Based on Robust Active Shape Model Matching
International Journal of Biomedical Imaging
title Lung Segmentation in 4D CT Volumes Based on Robust Active Shape Model Matching
title_full Lung Segmentation in 4D CT Volumes Based on Robust Active Shape Model Matching
title_fullStr Lung Segmentation in 4D CT Volumes Based on Robust Active Shape Model Matching
title_full_unstemmed Lung Segmentation in 4D CT Volumes Based on Robust Active Shape Model Matching
title_short Lung Segmentation in 4D CT Volumes Based on Robust Active Shape Model Matching
title_sort lung segmentation in 4d ct volumes based on robust active shape model matching
url http://dx.doi.org/10.1155/2015/125648
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AT reinhardrbeichel lungsegmentationin4dctvolumesbasedonrobustactiveshapemodelmatching