Angiogenin: biological role, mechanisms of action, and participation in oncogenesis

Angiogenin is a small polypeptide consisting of 123 amino acids involved in the processes of angiogenesis and tumorigenesis. This protein plays an important role in various physiological and pathological processes through the regulation of cell proliferation, survival, migration, invasion, and diffe...

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Main Authors: D. E. Mikhalev, S. N. Korotenko, A. Yu. Lomovskikh, O. D. Baydik
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2025-01-01
Series:Бюллетень сибирской медицины
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Online Access:https://bulletin.ssmu.ru/jour/article/view/5884
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author D. E. Mikhalev
S. N. Korotenko
A. Yu. Lomovskikh
O. D. Baydik
author_facet D. E. Mikhalev
S. N. Korotenko
A. Yu. Lomovskikh
O. D. Baydik
author_sort D. E. Mikhalev
collection DOAJ
description Angiogenin is a small polypeptide consisting of 123 amino acids involved in the processes of angiogenesis and tumorigenesis. This protein plays an important role in various physiological and pathological processes through the regulation of cell proliferation, survival, migration, invasion, and differentiation.The lecture presents data on angiogenin production and interaction with various proteins, describes mechanisms of its action, and shows its biological role in angiogenesis and oncogenesis. The literature search was carried out in the PubMed, Medline, Elibrary, Scopus, The Cochrane Library, and RSCI search engines.
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issn 1682-0363
1819-3684
language English
publishDate 2025-01-01
publisher Siberian State Medical University (Tomsk)
record_format Article
series Бюллетень сибирской медицины
spelling doaj-art-a2b5b9e8268e4d558df752a5a1eb90cf2025-08-20T03:02:06ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842025-01-0123416917610.20538/1682-0363-2024-4-169-1763125Angiogenin: biological role, mechanisms of action, and participation in oncogenesisD. E. Mikhalev0S. N. Korotenko1A. Yu. Lomovskikh2O. D. Baydik3Siberian State Medical UniversitySiberian State Medical UniversitySiberian State Medical UniversitySiberian State Medical UniversityAngiogenin is a small polypeptide consisting of 123 amino acids involved in the processes of angiogenesis and tumorigenesis. This protein plays an important role in various physiological and pathological processes through the regulation of cell proliferation, survival, migration, invasion, and differentiation.The lecture presents data on angiogenin production and interaction with various proteins, describes mechanisms of its action, and shows its biological role in angiogenesis and oncogenesis. The literature search was carried out in the PubMed, Medline, Elibrary, Scopus, The Cochrane Library, and RSCI search engines.https://bulletin.ssmu.ru/jour/article/view/5884angiogeninangiogenesiscarcinogenesisbiologically active substances
spellingShingle D. E. Mikhalev
S. N. Korotenko
A. Yu. Lomovskikh
O. D. Baydik
Angiogenin: biological role, mechanisms of action, and participation in oncogenesis
Бюллетень сибирской медицины
angiogenin
angiogenesis
carcinogenesis
biologically active substances
title Angiogenin: biological role, mechanisms of action, and participation in oncogenesis
title_full Angiogenin: biological role, mechanisms of action, and participation in oncogenesis
title_fullStr Angiogenin: biological role, mechanisms of action, and participation in oncogenesis
title_full_unstemmed Angiogenin: biological role, mechanisms of action, and participation in oncogenesis
title_short Angiogenin: biological role, mechanisms of action, and participation in oncogenesis
title_sort angiogenin biological role mechanisms of action and participation in oncogenesis
topic angiogenin
angiogenesis
carcinogenesis
biologically active substances
url https://bulletin.ssmu.ru/jour/article/view/5884
work_keys_str_mv AT demikhalev angiogeninbiologicalrolemechanismsofactionandparticipationinoncogenesis
AT snkorotenko angiogeninbiologicalrolemechanismsofactionandparticipationinoncogenesis
AT ayulomovskikh angiogeninbiologicalrolemechanismsofactionandparticipationinoncogenesis
AT odbaydik angiogeninbiologicalrolemechanismsofactionandparticipationinoncogenesis