Bartonella henselae Infective Pulmonic Valve Endocarditis Triggering ANCA-Associated Crescentic Necrotizing Glomerulonephritis

Bartonella species is the third leading cause of infective endocarditis–associated glomerulonephritis and the most common cause among culture-negative cases. Most cases involve tricuspid, aortic and mitral valves. We report an unusual case of pulmonic valve infective endocarditis causing acute kidne...

Full description

Saved in:
Bibliographic Details
Main Authors: Natalia Nombera-Aznaran, Christopher Blais, J. Martin Rodriguez, Yihan Wang, Juan Carlos Q. Velez
Format: Article
Language:English
Published: American College of Physicians 2025-05-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2024.0373
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Bartonella species is the third leading cause of infective endocarditis–associated glomerulonephritis and the most common cause among culture-negative cases. Most cases involve tricuspid, aortic and mitral valves. We report an unusual case of pulmonic valve infective endocarditis causing acute kidney injury due to antineutrophil cytoplasmic antibody–associated pauci-immune glomerulonephritis. Urinary sediment microscopy findings raised clinical suspicion before fever or other signs of infection appeared. The case also highlights the importance of recognition of histopathologic patterns of injury in infective endocarditis–associated glomerulonephritis, the caveats about testing for Bartonella species infections, and the diagnostic value of nuclear medicine in this setting.
ISSN:2767-7664