Islet organoids: a new hope for islet transplantation in diabetes

Islet organoids: a new hope for islet transplantation in diabetes

Diabetes mellitus, including Type 1 diabetes (T1D) and advanced Type 2 diabetes (T2D), remains a major global health challenge due to the destruction or dysfunction of insulin-producing β-cells. Islet transplantation offers a promising therapeutic strategy. However, it is limited by organ shortage g...

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Bibliographic Details
Main Authors:	Xuemei Yu, Chengkong Liu, Zheng Kuang, Siyuan Song, Limin Tian, Yi Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Immunology
Subjects:	islet organoids diabetes treatment Procr+ progenitors chemically induced pluripotent stem cells (CiPSCs) endoderm stem cells (EnSCs) β-cell regeneration
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1540209/full
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