Listeria monocytogenes Cerebritis and Infective Endocarditis in an Immunocompetent Adult: A Rare Clinical Manifestation

Cerebritis and infective endocarditis caused by Listeria monocytogenes are very rare. A 56-year-old man presented with slurring of speech and generalized body weakness of 1 week duration. He did not have any past medical history. On systemic examination, he had mild slurring of speech and facial asy...

Full description

Saved in:
Bibliographic Details
Main Authors: Shalini A. Mohan, Zharif Sufyaan
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2023/7405556
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832546753432256512
author Shalini A. Mohan
Zharif Sufyaan
author_facet Shalini A. Mohan
Zharif Sufyaan
author_sort Shalini A. Mohan
collection DOAJ
description Cerebritis and infective endocarditis caused by Listeria monocytogenes are very rare. A 56-year-old man presented with slurring of speech and generalized body weakness of 1 week duration. He did not have any past medical history. On systemic examination, he had mild slurring of speech and facial asymmetry and was initially treated for multifocal chronic cerebral infarcts. Listeria monocytogenes was isolated from blood culture on day 5 of admission. A diagnosis of neurolisteriosis was made as contrast-enhanced-computed tomography (CECT) of the brain showed right frontal cerebritis. He was treated with intravenous benzyl penicillin. His general condition was improving until day 13 of hospitalization whereby he developed haemoptysis and severe Type 1 respiratory failure requiring reintubation. An urgent transthoracic echocardiogram revealed a large vegetation at the anterior mitral valve leaflet measuring 2.01 cm. No active arterial bleeding was seen on computed tomography angiography (CTA) of the thorax. Magnetic resonance imaging (MRI) of the brain showed evidence of right frontal cerebritis. He continued to deteriorate and succumbed to his illness after 3 weeks of hospitalization. Clinicians should be aware of such an occurrence and prompt recognition and adequate treatment are necessary in cases of Listeria monocytogenes cerebritis and infective endocarditis as both are deadly entities.
format Article
id doaj-art-a294ad189f79401189f88b2f221c5fd0
institution Kabale University
issn 2090-6633
language English
publishDate 2023-01-01
publisher Wiley
record_format Article
series Case Reports in Infectious Diseases
spelling doaj-art-a294ad189f79401189f88b2f221c5fd02025-02-03T06:47:21ZengWileyCase Reports in Infectious Diseases2090-66332023-01-01202310.1155/2023/7405556Listeria monocytogenes Cerebritis and Infective Endocarditis in an Immunocompetent Adult: A Rare Clinical ManifestationShalini A. Mohan0Zharif Sufyaan1Department of Internal MedicineDepartment of Internal MedicineCerebritis and infective endocarditis caused by Listeria monocytogenes are very rare. A 56-year-old man presented with slurring of speech and generalized body weakness of 1 week duration. He did not have any past medical history. On systemic examination, he had mild slurring of speech and facial asymmetry and was initially treated for multifocal chronic cerebral infarcts. Listeria monocytogenes was isolated from blood culture on day 5 of admission. A diagnosis of neurolisteriosis was made as contrast-enhanced-computed tomography (CECT) of the brain showed right frontal cerebritis. He was treated with intravenous benzyl penicillin. His general condition was improving until day 13 of hospitalization whereby he developed haemoptysis and severe Type 1 respiratory failure requiring reintubation. An urgent transthoracic echocardiogram revealed a large vegetation at the anterior mitral valve leaflet measuring 2.01 cm. No active arterial bleeding was seen on computed tomography angiography (CTA) of the thorax. Magnetic resonance imaging (MRI) of the brain showed evidence of right frontal cerebritis. He continued to deteriorate and succumbed to his illness after 3 weeks of hospitalization. Clinicians should be aware of such an occurrence and prompt recognition and adequate treatment are necessary in cases of Listeria monocytogenes cerebritis and infective endocarditis as both are deadly entities.http://dx.doi.org/10.1155/2023/7405556
spellingShingle Shalini A. Mohan
Zharif Sufyaan
Listeria monocytogenes Cerebritis and Infective Endocarditis in an Immunocompetent Adult: A Rare Clinical Manifestation
Case Reports in Infectious Diseases
title Listeria monocytogenes Cerebritis and Infective Endocarditis in an Immunocompetent Adult: A Rare Clinical Manifestation
title_full Listeria monocytogenes Cerebritis and Infective Endocarditis in an Immunocompetent Adult: A Rare Clinical Manifestation
title_fullStr Listeria monocytogenes Cerebritis and Infective Endocarditis in an Immunocompetent Adult: A Rare Clinical Manifestation
title_full_unstemmed Listeria monocytogenes Cerebritis and Infective Endocarditis in an Immunocompetent Adult: A Rare Clinical Manifestation
title_short Listeria monocytogenes Cerebritis and Infective Endocarditis in an Immunocompetent Adult: A Rare Clinical Manifestation
title_sort listeria monocytogenes cerebritis and infective endocarditis in an immunocompetent adult a rare clinical manifestation
url http://dx.doi.org/10.1155/2023/7405556
work_keys_str_mv AT shaliniamohan listeriamonocytogenescerebritisandinfectiveendocarditisinanimmunocompetentadultarareclinicalmanifestation
AT zharifsufyaan listeriamonocytogenescerebritisandinfectiveendocarditisinanimmunocompetentadultarareclinicalmanifestation