Clinical-epidemiological profile, risk factors and quality of life of patients with meibomian gland dysfunction
ABSTRACT Objective: To investigate clinical-epidemiological profile, risk factors, and quality of life of patients with meibomian gland dysfunction. Methods: A total of 108 patients were prospectively studied. Symptoms of dry eye, eyelid disorders and secretory function were analyzed. Laboratorial...
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Sociedade Brasileira de Oftalmologia
2025-06-01
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| Series: | Revista Brasileira de Oftalmologia |
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| _version_ | 1850215196234088448 |
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| author | Thaissa Faloppa Duarte Rubens Camargo Siqueira |
| author_facet | Thaissa Faloppa Duarte Rubens Camargo Siqueira |
| author_sort | Thaissa Faloppa Duarte |
| collection | DOAJ |
| description | ABSTRACT Objective: To investigate clinical-epidemiological profile, risk factors, and quality of life of patients with meibomian gland dysfunction. Methods: A total of 108 patients were prospectively studied. Symptoms of dry eye, eyelid disorders and secretory function were analyzed. Laboratorial exams included fasting glucose, glycated hemoglobin, cholesterol, and triglycerides. Quality of life was analyzed using the Ocular Surface Disease Index©. Results: Mean age was 53.6 ± 17.9 years, 69.4% were females, 82.7% with gynecological history, 46.3% with cardiovascular history, and 80.6% had family history of cardiovascular disease. Symptoms were mild (28.7%) or moderate (38%), most of the patients showed slightly thickened eyelid margin (44.4%) and all functional glands (50.9%). Regarding clinical severity of patients, 34.3% were mild, 34.3% were moderate, and 31.4% were severe. In 11.3% and 19.6% of the patients, high fasting glucose and glycated hemoglobin levels, respectively, were found. There was association among severity and gynecological (p=0.001), cardiovascular (p=0.006) history, and quality of life (p<0.001). Conclusion: Meibomian gland dysfunction was predominant in female and in the fifth decade of life. Most patients had all functional Meibomian glands and signs of evaporative dry eye. Glucose and lipid profile levels may be altered in these patients. Most patients had worse life quality. There was association among clinical severity and gynecological, cardiovascular history, and quality of life. |
| format | Article |
| id | doaj-art-a2901e7e07884c4b8108e8155eb7f11a |
| institution | OA Journals |
| issn | 1982-8551 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Sociedade Brasileira de Oftalmologia |
| record_format | Article |
| series | Revista Brasileira de Oftalmologia |
| spelling | doaj-art-a2901e7e07884c4b8108e8155eb7f11a2025-08-20T02:08:42ZengSociedade Brasileira de OftalmologiaRevista Brasileira de Oftalmologia1982-85512025-06-018410.37039/1982.8551.20250033Clinical-epidemiological profile, risk factors and quality of life of patients with meibomian gland dysfunctionThaissa Faloppa Duartehttps://orcid.org/0000-0003-2233-3749Rubens Camargo Siqueirahttps://orcid.org/0000-0003-4563-1570ABSTRACT Objective: To investigate clinical-epidemiological profile, risk factors, and quality of life of patients with meibomian gland dysfunction. Methods: A total of 108 patients were prospectively studied. Symptoms of dry eye, eyelid disorders and secretory function were analyzed. Laboratorial exams included fasting glucose, glycated hemoglobin, cholesterol, and triglycerides. Quality of life was analyzed using the Ocular Surface Disease Index©. Results: Mean age was 53.6 ± 17.9 years, 69.4% were females, 82.7% with gynecological history, 46.3% with cardiovascular history, and 80.6% had family history of cardiovascular disease. Symptoms were mild (28.7%) or moderate (38%), most of the patients showed slightly thickened eyelid margin (44.4%) and all functional glands (50.9%). Regarding clinical severity of patients, 34.3% were mild, 34.3% were moderate, and 31.4% were severe. In 11.3% and 19.6% of the patients, high fasting glucose and glycated hemoglobin levels, respectively, were found. There was association among severity and gynecological (p=0.001), cardiovascular (p=0.006) history, and quality of life (p<0.001). Conclusion: Meibomian gland dysfunction was predominant in female and in the fifth decade of life. Most patients had all functional Meibomian glands and signs of evaporative dry eye. Glucose and lipid profile levels may be altered in these patients. Most patients had worse life quality. There was association among clinical severity and gynecological, cardiovascular history, and quality of life.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802025000100216&lng=en&tlng=enDry eye syndromesMeibomian gland dysfunctionEpidemiologyRisk factorsQuality of life |
| spellingShingle | Thaissa Faloppa Duarte Rubens Camargo Siqueira Clinical-epidemiological profile, risk factors and quality of life of patients with meibomian gland dysfunction Revista Brasileira de Oftalmologia Dry eye syndromes Meibomian gland dysfunction Epidemiology Risk factors Quality of life |
| title | Clinical-epidemiological profile, risk factors and quality of life of patients with meibomian gland dysfunction |
| title_full | Clinical-epidemiological profile, risk factors and quality of life of patients with meibomian gland dysfunction |
| title_fullStr | Clinical-epidemiological profile, risk factors and quality of life of patients with meibomian gland dysfunction |
| title_full_unstemmed | Clinical-epidemiological profile, risk factors and quality of life of patients with meibomian gland dysfunction |
| title_short | Clinical-epidemiological profile, risk factors and quality of life of patients with meibomian gland dysfunction |
| title_sort | clinical epidemiological profile risk factors and quality of life of patients with meibomian gland dysfunction |
| topic | Dry eye syndromes Meibomian gland dysfunction Epidemiology Risk factors Quality of life |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802025000100216&lng=en&tlng=en |
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