Ionic Liquid 1-Octyl-3-Methylimidazolium (M8OI) Is Mono-Oxygenated by CYP3A4 and CYP3A5 in Adult Human Liver

Environmental sampling around a landfill site in the UK previously identified the methylimidazolium ionic liquid, 1-octyl-3-methylimidazolium (M8OI), in the soil. More recently, M8OI was shown to be detectable in sera from 5/20 PBC patients and 1/10 controls and to be oxidised on the alkyl chain in...

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Bibliographic Details
Main Authors: Alistair C. Leitch, Tarek M. Abdelghany, Alex Charlton, Martin Cooke, Matthew C. Wright
Format: Article
Language:English
Published: MDPI AG 2024-07-01
Series:Journal of Xenobiotics
Subjects:
Online Access:https://www.mdpi.com/2039-4713/14/3/50
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