Synthesis and Structure–Activity Relationship (SAR) Studies on New 4-Aminoquinoline-Hydrazones and Isatin Hybrids as Promising Antibacterial Agents

Synthesis and Structure–Activity Relationship (SAR) Studies on New 4-Aminoquinoline-Hydrazones and Isatin Hybrids as Promising Antibacterial Agents

In response to the escalating crisis of antimicrobial resistance (AMR), there is an urgent need to research and develop novel antibiotics. This study presents the synthesis and assessment of innovative 4-aminoquinoline-benzohydrazide-based molecular hybrids bearing aryl aldehydes (<b>HD1-23<...

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Bibliographic Details
Main Authors: Ayesha Ubaid, Mohd. Shakir, Asghar Ali, Sobia Khan, Jihad Alrehaili, Razique Anwer, Mohammad Abid
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Molecules
Subjects:
antimicrobial resistance <i>S. aureus</i>
MIC
quinoline–isatin hybrids
biofilm
bactericidal
MDR
Online Access:https://www.mdpi.com/1420-3049/29/23/5777
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