Antimicrobial Zn<sup>2+</sup>-Carboxymethyl Chitosan Cryogel for Controlled Loading and Release of Ciprofloxacin via Coordination Bonds

Antimicrobial Zn<sup>2+</sup>-Carboxymethyl Chitosan Cryogel for Controlled Loading and Release of Ciprofloxacin via Coordination Bonds

The local application of broad-spectrum antibiotics via polymeric drug delivery systems is a promising alternative to their systemic administration in wound healing, prevention and treatment of infections associated with surgical implants. However, low and poorly controlled loading efficiency and 10...

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Bibliographic Details
Main Authors: Svetlana Bratskaya, Andrey Boroda, Tamara Bogomaz, Yuliya Privar, Mariya Maiorova, Daniil Malyshev, Anastasiia Shindina, Anna Skatova, Roman Goncharuk
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Gels
Subjects:
carboxymethyl chitosan
zinc
ciprofloxacin
drug release
cytotoxicity
FT-IR spectroscopy
Online Access:https://www.mdpi.com/2310-2861/10/12/841
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