Toll-like receptor 3 activation enhances antitumor immune response in lung adenocarcinoma through NF-κB signaling pathway

Toll-like receptor 3 activation enhances antitumor immune response in lung adenocarcinoma through NF-κB signaling pathway

BackgroundToll-like receptor 3 (TLR3) is a pattern recognition receptor known to play a crucial role in the immune response to cancer. However, its effect on the efficacy of immunotherapy in lung adenocarcinoma (LUAD) remains unclear. This study aims to investigate the role of TLR3 in LUAD by examin...

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Bibliographic Details
Main Authors: Ang Li, Man Luo, Xiyao Liu, Hongjiao Wu, Xiaoguang Liu, Zhi Zhang, Xuemei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
toll-like receptor 3
lung adenocarcinoma
PD-L1
tumor microenvironment
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1585747/full
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