Drosophila Piwi distinguishes transposons from mRNAs by piRNA complementarity and abundance

Summary: Piwi-interacting RNAs (piRNAs) are the main repressors of transposable elements (TEs) in animal germlines. In Drosophila, Piwi-piRNA complexes associate with nascent TE transcripts to drive heterochromatin formation and TE repression. However, previous studies have shown that Piwi also asso...

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Main Authors: Masaru Ariura, Therese Solberg, Hirotsugu Ishizu, Hazuki Takahashi, Piero Carninci, Haruhiko Siomi, Yuka W. Iwasaki
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724013718
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