A molecular dynamics study of membrane positioning for 7-transmembrane RGS proteins to modulate G-protein-mediated signaling in plants

A molecular dynamics study of membrane positioning for 7-transmembrane RGS proteins to modulate G-protein-mediated signaling in plants

Protein phosphorylation regulates G protein signaling in plants. AtRGS1 primarily modulates AtGPA1, the canonical Gα subunit in the heterotrimeric G protein complex. AtRGS1 possesses both a seven-transmembrane (7TM) domain connected to a cytoplasmic Regulator of G Protein Signaling domain (RGS box d...

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Bibliographic Details
Main Authors: Celio Cabral Oliveira, Eduardo Bassi Simoni, Mariana Abrahão Bueno Morais, Elizabeth Pacheco Batista Fontes, Pedro A. Braga dos Reis, Daisuke Urano, Alan M. Jones
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Arabidopsis
Regulator of G protein signaling (RGS)
Linker domain
Heterotrimeric G protein
Molecular dynamics
Protein evolution
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037025001333
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