Mice Lacking beta2-Integrin Function Remain Glucose Tolerant in Spite of Insulin Resistance, Neutrophil Infiltration and Inflammation.
Beta2-integrins are important in leukocyte trafficking and function, and are regulated through the binding of cytoplasmic proteins, such as kindlin-3, to their intracellular domain. Here, we investigate the involvement of beta2-integrins in the regulation of metabolic disease using mice where the ki...
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| Main Authors: | Paul J Meakin, Vicky L Morrison, Claire C Sneddon, Terhi Savinko, Liisa Uotila, Susan M Jalicy, Jennie L Gabriel, Li Kang, Michael L J Ashford, Susanna C Fagerholm |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2015-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0138872 |
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