A simplified and reproducible ex vivo model of cold and ischemia-reperfusion injury

A simplified and reproducible ex vivo model of cold and ischemia-reperfusion injury

Both cold stress and ischemia-reperfusion injury significantly contribute to poor prognosis after liver transplantation (LT). However, limited animal models incorporating both stimuli hinder the advancement of transplant-related research. Here, a simplified and reproducible isolated perfused liver m...

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Bibliographic Details
Main Authors:	Lele Zhang, Mingjie Ding, Ying Zhu, Zhiping Yan, Wenzhi Guo
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2025-06-01
Series:	Liver Research
Subjects:	Liver transplantation Animal model Ischemia-reperfusion injury Static cold storage (SCS) Normothermic machine perfusion (NMP) Ex vivo rat model
Online Access:	http://www.sciencedirect.com/science/article/pii/S2542568425000303
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