HIGH LEVEL OF IL -1 RECEPTOR ANTAGONIST AS A LETHALITY FACTOR IN PATIENTS WITH SURGICAL SEPSIS
Absract. The data are presented that concern the levels of IL-1 receptor antagonist (IL-1 Ra) in blood serum of twenty-five patients with severe surgical sepsis. Sixteen patients recovered from the condition, whereas lethal outcome was registered in nine cases. The study was performed by means of im...
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| Format: | Article |
| Language: | Russian |
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St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2014-07-01
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| Series: | Медицинская иммунология |
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| Online Access: | https://www.mimmun.ru/mimmun/article/view/323 |
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| author | V. V. Grebenyuk G. A. Makarova N. V. Yusan |
| author_facet | V. V. Grebenyuk G. A. Makarova N. V. Yusan |
| author_sort | V. V. Grebenyuk |
| collection | DOAJ |
| description | Absract. The data are presented that concern the levels of IL-1 receptor antagonist (IL-1 Ra) in blood serum of twenty-five patients with severe surgical sepsis. Sixteen patients recovered from the condition, whereas lethal outcome was registered in nine cases. The study was performed by means of immunoassay, using «IFA-Best IL-1 Ra» kits supplied by the Vector-Best firm. Only three patients showed IL-1 Ra contents within normal limits, whereas others exhibited marked increase in IL-1 Ra levels, up to a mean of 2443.656±382.85 pg/ml (normal range, 50 to 1000 pg/ml). |
| format | Article |
| id | doaj-art-a243c5e80256459daf478412a589984b |
| institution | Kabale University |
| issn | 1563-0625 2313-741X |
| language | Russian |
| publishDate | 2014-07-01 |
| publisher | St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists |
| record_format | Article |
| series | Медицинская иммунология |
| spelling | doaj-art-a243c5e80256459daf478412a589984b2025-08-20T04:00:09ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-07-01112-328728810.15789/1563-0625-2009-2-3-287-288320HIGH LEVEL OF IL -1 RECEPTOR ANTAGONIST AS A LETHALITY FACTOR IN PATIENTS WITH SURGICAL SEPSISV. V. Grebenyuk0G. A. Makarova1N. V. Yusan2ГОУ ВПО «Амурская государственная медицинская академия», г. БлаговещенскГУ «Дальневосточный научный центр физиологии и патологии дыхания СО РАМН», г. БлаговещенскГОУ ВПО «Амурская государственная медицинская академия», г. БлаговещенскAbsract. The data are presented that concern the levels of IL-1 receptor antagonist (IL-1 Ra) in blood serum of twenty-five patients with severe surgical sepsis. Sixteen patients recovered from the condition, whereas lethal outcome was registered in nine cases. The study was performed by means of immunoassay, using «IFA-Best IL-1 Ra» kits supplied by the Vector-Best firm. Only three patients showed IL-1 Ra contents within normal limits, whereas others exhibited marked increase in IL-1 Ra levels, up to a mean of 2443.656±382.85 pg/ml (normal range, 50 to 1000 pg/ml).https://www.mimmun.ru/mimmun/article/view/323surgical sepsisil-1 raelisalethal outcome |
| spellingShingle | V. V. Grebenyuk G. A. Makarova N. V. Yusan HIGH LEVEL OF IL -1 RECEPTOR ANTAGONIST AS A LETHALITY FACTOR IN PATIENTS WITH SURGICAL SEPSIS Медицинская иммунология surgical sepsis il-1 ra elisa lethal outcome |
| title | HIGH LEVEL OF IL -1 RECEPTOR ANTAGONIST AS A LETHALITY FACTOR IN PATIENTS WITH SURGICAL SEPSIS |
| title_full | HIGH LEVEL OF IL -1 RECEPTOR ANTAGONIST AS A LETHALITY FACTOR IN PATIENTS WITH SURGICAL SEPSIS |
| title_fullStr | HIGH LEVEL OF IL -1 RECEPTOR ANTAGONIST AS A LETHALITY FACTOR IN PATIENTS WITH SURGICAL SEPSIS |
| title_full_unstemmed | HIGH LEVEL OF IL -1 RECEPTOR ANTAGONIST AS A LETHALITY FACTOR IN PATIENTS WITH SURGICAL SEPSIS |
| title_short | HIGH LEVEL OF IL -1 RECEPTOR ANTAGONIST AS A LETHALITY FACTOR IN PATIENTS WITH SURGICAL SEPSIS |
| title_sort | high level of il 1 receptor antagonist as a lethality factor in patients with surgical sepsis |
| topic | surgical sepsis il-1 ra elisa lethal outcome |
| url | https://www.mimmun.ru/mimmun/article/view/323 |
| work_keys_str_mv | AT vvgrebenyuk highlevelofil1receptorantagonistasalethalityfactorinpatientswithsurgicalsepsis AT gamakarova highlevelofil1receptorantagonistasalethalityfactorinpatientswithsurgicalsepsis AT nvyusan highlevelofil1receptorantagonistasalethalityfactorinpatientswithsurgicalsepsis |