cGAS-like receptors drive a systemic STING-dependent host response in Drosophila

cGAS-like receptors drive a systemic STING-dependent host response in Drosophila

Summary: cGAS-like receptor (cGLR)-stimulator of interferon genes (STING) recently emerged as an important pathway controlling viral infections in invertebrates. However, its exact contribution at the organismal level remains uncharacterized. Here, we use STING::GFP knockin reporter Drosophila flies...

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Main Authors: Xianlong Ai, Huimin Deng, Xiaoyan Li, Ziming Wei, Yuqiang Chen, Ting Yin, Junhui Zhang, Jingxian Huang, Haoming Li, Xiaoqing Lin, Long Tan, Di Chen, Xiaohan Zhang, Xiuqing Zhang, Carine Meignin, Jean-Luc Imler, Hua Cai
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724014323
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