Multiomics analysis reveals microbial diversity and activity through spontaneous fermentation of Theobroma cacao

To gain insight into the active microbiota during spontaneous fermentation of Theobroma cacao L., this study assessed protein diversity during 120 h using a combined metabarconding and metaproteomics approach. During the first days of fermentation, most of the peptides were associated with T. cacao...

Full description

Saved in:
Bibliographic Details
Main Authors: Ynara da Costa Fonseca, Celina Eugenio Bahule, Hector Herrera, Luiza Helena da Silva Martins, Alessandra Santos Lopes, Juliana Silva Cassoli, Felipe Costa Trindade, Isa Rebecca Chagas da Costa, Paulo Henrique de Oliveira Costa, Guilherme Oliveira, Rafael Borges da Silva Valadares
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024165735
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850108497108140032
author Ynara da Costa Fonseca
Celina Eugenio Bahule
Hector Herrera
Luiza Helena da Silva Martins
Alessandra Santos Lopes
Juliana Silva Cassoli
Felipe Costa Trindade
Isa Rebecca Chagas da Costa
Paulo Henrique de Oliveira Costa
Guilherme Oliveira
Rafael Borges da Silva Valadares
author_facet Ynara da Costa Fonseca
Celina Eugenio Bahule
Hector Herrera
Luiza Helena da Silva Martins
Alessandra Santos Lopes
Juliana Silva Cassoli
Felipe Costa Trindade
Isa Rebecca Chagas da Costa
Paulo Henrique de Oliveira Costa
Guilherme Oliveira
Rafael Borges da Silva Valadares
author_sort Ynara da Costa Fonseca
collection DOAJ
description To gain insight into the active microbiota during spontaneous fermentation of Theobroma cacao L., this study assessed protein diversity during 120 h using a combined metabarconding and metaproteomics approach. During the first days of fermentation, most of the peptides were associated with T. cacao and yeast (0–72 h). Peptides associated with bacteria became more abundant after 72 h of fermentation, coinciding with a decrease in peptides associated with cocoa (96–120 h). In addition to the known microorganisms involved in fermentation, such as Saccharomyces, Lactobacillus and Acetobacter, novel genera were also metabolically active, including Microvirga, Inquilinus, Candolleomyces and Lasiodiplodia.. The results showed a consistency in the main genera detected by both techniques, but the identification of unexplored genera such as Inquilinus, Microvirga, Cyphellophora and Ashbya gossypii, among others, suggests that this omics approach needs to be used together for more comprehensive results on spontaneous fermentation. In conclusion, studies combining techniques such as metabarcoding and metaproteomics should be considered in fermentation studies, as a single technique would result in omissions regarding the activity of certain microorganisms that may be important for the course of spontaneous fermentation.
format Article
id doaj-art-a22dfcf0e4bf43ea96bc4f97dd9ab9ef
institution OA Journals
issn 2405-8440
language English
publishDate 2024-12-01
publisher Elsevier
record_format Article
series Heliyon
spelling doaj-art-a22dfcf0e4bf43ea96bc4f97dd9ab9ef2025-08-20T02:38:21ZengElsevierHeliyon2405-84402024-12-011023e4054210.1016/j.heliyon.2024.e40542Multiomics analysis reveals microbial diversity and activity through spontaneous fermentation of Theobroma cacaoYnara da Costa Fonseca0Celina Eugenio Bahule1Hector Herrera2Luiza Helena da Silva Martins3Alessandra Santos Lopes4Juliana Silva Cassoli5Felipe Costa Trindade6Isa Rebecca Chagas da Costa7Paulo Henrique de Oliveira Costa8Guilherme Oliveira9Rafael Borges da Silva Valadares10Graduate Program in Agricultural Applied Biotechnology, Federal Rural University of Amazonia, President Tancredo Neves Ave, 2501, Belém, CEP 66.077-830, Brazil; Vale Institute of Technology, Boaventura da Silva Street 955, Belém, CEP 66050-090, BrazilCenter of Studies in Science and Technology (NECET), Rovuma University, Niassa Branch, Lichinga, MozambiqueDepartamento de Ciencias Forestales, Facultad de Ciencias Agropecuarias y Medioambiente, Universidad de La Frontera, Temuco, 4811230, Chile; Center for Biodiversity and Ecological Sustainability (C-BEST), Facultad de Ciencias Agropecuarias y Medioambiente, Universidad de La Frontera, ChileInstitute of Animal Health and Production, Federal Rural University of Amazonia, President Tancredo Neves Ave., 2501, Belém, CEP 66077-830, BrazilFaculty of Food Engineering, Institute of Technology, Federal University of Pará, Belém, CEP 66075-110, BrazilLaboratory of Omics Sciences, Institute of Biological Sciences, Guamá Campus, Federal University of Pará, 66075-110, Belém, BrazilVale Institute of Technology, Boaventura da Silva Street 955, Belém, CEP 66050-090, BrazilVale Institute of Technology, Boaventura da Silva Street 955, Belém, CEP 66050-090, BrazilVale Institute of Technology, Boaventura da Silva Street 955, Belém, CEP 66050-090, BrazilVale Institute of Technology, Boaventura da Silva Street 955, Belém, CEP 66050-090, BrazilVale Institute of Technology, Boaventura da Silva Street 955, Belém, CEP 66050-090, Brazil; Corresponding author. Vale Institute of Technology Sustainable Development, Rua Boaventura da Silva 955, Umarizal, CEP 66055-090, Belém, PA, Brazil.To gain insight into the active microbiota during spontaneous fermentation of Theobroma cacao L., this study assessed protein diversity during 120 h using a combined metabarconding and metaproteomics approach. During the first days of fermentation, most of the peptides were associated with T. cacao and yeast (0–72 h). Peptides associated with bacteria became more abundant after 72 h of fermentation, coinciding with a decrease in peptides associated with cocoa (96–120 h). In addition to the known microorganisms involved in fermentation, such as Saccharomyces, Lactobacillus and Acetobacter, novel genera were also metabolically active, including Microvirga, Inquilinus, Candolleomyces and Lasiodiplodia.. The results showed a consistency in the main genera detected by both techniques, but the identification of unexplored genera such as Inquilinus, Microvirga, Cyphellophora and Ashbya gossypii, among others, suggests that this omics approach needs to be used together for more comprehensive results on spontaneous fermentation. In conclusion, studies combining techniques such as metabarcoding and metaproteomics should be considered in fermentation studies, as a single technique would result in omissions regarding the activity of certain microorganisms that may be important for the course of spontaneous fermentation.http://www.sciencedirect.com/science/article/pii/S2405844024165735BacteriaCocoaMetabarcodingMetaproteomics
spellingShingle Ynara da Costa Fonseca
Celina Eugenio Bahule
Hector Herrera
Luiza Helena da Silva Martins
Alessandra Santos Lopes
Juliana Silva Cassoli
Felipe Costa Trindade
Isa Rebecca Chagas da Costa
Paulo Henrique de Oliveira Costa
Guilherme Oliveira
Rafael Borges da Silva Valadares
Multiomics analysis reveals microbial diversity and activity through spontaneous fermentation of Theobroma cacao
Heliyon
Bacteria
Cocoa
Metabarcoding
Metaproteomics
title Multiomics analysis reveals microbial diversity and activity through spontaneous fermentation of Theobroma cacao
title_full Multiomics analysis reveals microbial diversity and activity through spontaneous fermentation of Theobroma cacao
title_fullStr Multiomics analysis reveals microbial diversity and activity through spontaneous fermentation of Theobroma cacao
title_full_unstemmed Multiomics analysis reveals microbial diversity and activity through spontaneous fermentation of Theobroma cacao
title_short Multiomics analysis reveals microbial diversity and activity through spontaneous fermentation of Theobroma cacao
title_sort multiomics analysis reveals microbial diversity and activity through spontaneous fermentation of theobroma cacao
topic Bacteria
Cocoa
Metabarcoding
Metaproteomics
url http://www.sciencedirect.com/science/article/pii/S2405844024165735
work_keys_str_mv AT ynaradacostafonseca multiomicsanalysisrevealsmicrobialdiversityandactivitythroughspontaneousfermentationoftheobromacacao
AT celinaeugeniobahule multiomicsanalysisrevealsmicrobialdiversityandactivitythroughspontaneousfermentationoftheobromacacao
AT hectorherrera multiomicsanalysisrevealsmicrobialdiversityandactivitythroughspontaneousfermentationoftheobromacacao
AT luizahelenadasilvamartins multiomicsanalysisrevealsmicrobialdiversityandactivitythroughspontaneousfermentationoftheobromacacao
AT alessandrasantoslopes multiomicsanalysisrevealsmicrobialdiversityandactivitythroughspontaneousfermentationoftheobromacacao
AT julianasilvacassoli multiomicsanalysisrevealsmicrobialdiversityandactivitythroughspontaneousfermentationoftheobromacacao
AT felipecostatrindade multiomicsanalysisrevealsmicrobialdiversityandactivitythroughspontaneousfermentationoftheobromacacao
AT isarebeccachagasdacosta multiomicsanalysisrevealsmicrobialdiversityandactivitythroughspontaneousfermentationoftheobromacacao
AT paulohenriquedeoliveiracosta multiomicsanalysisrevealsmicrobialdiversityandactivitythroughspontaneousfermentationoftheobromacacao
AT guilhermeoliveira multiomicsanalysisrevealsmicrobialdiversityandactivitythroughspontaneousfermentationoftheobromacacao
AT rafaelborgesdasilvavaladares multiomicsanalysisrevealsmicrobialdiversityandactivitythroughspontaneousfermentationoftheobromacacao