Mechanobiological mechanism of cyclic stretch-induced cell columnarization
Summary: In vivo, epithelial cells maintain structural integrity under dynamic mechanical perturbations. To study this, we treated various epithelial cell lines with long-term cyclic stretch (CS). Surprisingly, cells transitioned from cuboidal to columnar shape (columnarization) in MDCK cells, while...
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| Main Authors: | Lun-Wei Lee, Gang-Hui Lee, I-Hsiu Su, Chia-Hsuan Lu, Keng-Hui Lin, Fu-Lai Wen, Ming-Jer Tang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-05-01
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| Series: | Cell Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124725004334 |
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