Deguelin’s Anticancer Bioactivity: Challenges and Opportunities in Medicinal Chemistry

Deguelin’s Anticancer Bioactivity: Challenges and Opportunities in Medicinal Chemistry

Deguelin is a natural isoflavone derived from the rotenone family, commonly found in plants belonging to the Derris and Grifola genera. Comprehensive research has underscored its considerable promise in oncological treatment. Deguelin demonstrates anticancer activity by suppressing cell proliferatio...

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Bibliographic Details
Main Authors:	Wenjie Jiang, Jing Zeng, Li Guo, Jianyou Shi, Yang Lei
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Series:	Frontiers in Pharmacology
Subjects:	deguelin deguelin derivatives cancer heat-shock proteins structure-activity relationship HSP90 inhibitor
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1571452/full
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