Creatine supplementation and muscle-brain axis: a new possible mechanism?

The brain and skeletal muscle have a high energy demand, of which creatine is an important regulator. Creatine acts as both a spatial and temporal energy buffer and reduces oxidative stress and inflammation. Creatine supplementation is well-recognized to enhance exercise performance, muscular streng...

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Bibliographic Details
Main Authors: Felipe Ribeiro, Scott C. Forbes, Darren G. Candow, Pedro Perim, Fabio Santos Lira, Antonio Herbert Lancha, José C. Rosa Neto
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Nutrition
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Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2025.1579204/full
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