Elucidating the role of pyrimidine metabolism in prostate cancer and its therapeutic implications
Abstract Our study aims to investigate the role of pyrimidine metabolism in prostate cancer and its associations with the immune microenvironment, drug sensitivity, and tumor mutation burden. Through transcriptomic and single-cell RNA sequencing analyses, we explored metabolic pathway enrichment, im...
Saved in:
Main Authors: | Liang Huang, Yu Xie, Shusuan Jiang, Kan Liu, Zhihao Ming, Hong Shan |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
|
Series: | Scientific Reports |
Subjects: | |
Online Access: | https://doi.org/10.1038/s41598-025-86052-5 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Identification of pyrimidine metabolism-based molecular subtypes and prognostic signature to predict immune landscape and guide clinical treatment in prostate cancer
by: Yu-Zhong Yu, et al.
Published: (2025-12-01) -
Metabolic reprogramming in cancer: Mechanisms and therapeutics
by: Shiqi Nong, et al.
Published: (2023-04-01) -
Research progresses and hotspots on glucose metabolic reprogramming in breast cancer: a bibliometric analysis over the past two decades
by: Lei Huang, et al.
Published: (2025-01-01) -
Metabolic reprogramming and immunological changes in the microenvironment of esophageal cancer: future directions and prospects
by: Zhi-Xun Guo, et al.
Published: (2025-01-01) -
Targeting glycolysis: exploring a new frontier in glioblastoma therapy
by: Lu Yang, et al.
Published: (2025-01-01)