Falsely Elevated 25-Hydroxy-Vitamin D Levels in Patients with Hypercalcemia
Symptomatic hypercalcemia is a commonly encountered clinical scenario. Though it is important to collect detailed history to find clinical clues connecting to the etiology of hypercalcemia, the diagnostic workup of hypercalcemia depends heavily on laboratory analysis. Accurate measurement of the par...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2020/8873506 |
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| _version_ | 1832553488656105472 |
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| author | Moon Kyung Choi Prapaipan Putthapiban Patamaporn Lekprasert |
| author_facet | Moon Kyung Choi Prapaipan Putthapiban Patamaporn Lekprasert |
| author_sort | Moon Kyung Choi |
| collection | DOAJ |
| description | Symptomatic hypercalcemia is a commonly encountered clinical scenario. Though it is important to collect detailed history to find clinical clues connecting to the etiology of hypercalcemia, the diagnostic workup of hypercalcemia depends heavily on laboratory analysis. Accurate measurement of the parathyroid hormone and vitamin D levels is essential. However, commercial laboratory measurement of vitamin D levels can be erroneous in the setting of abundant paraprotein in the serum. One of the most common conditions that can cause an increased amount of paraproteins is multiple myeloma. We report 2 cases of falsely elevated 25-hydroxy-vitamin D levels in patients presenting with hypercalcemia and an underlying diagnosis of MM. |
| format | Article |
| id | doaj-art-a20004f709b14693acc08ae8604c9fb4 |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-a20004f709b14693acc08ae8604c9fb42025-02-03T05:53:53ZengWileyCase Reports in Endocrinology2090-65012090-651X2020-01-01202010.1155/2020/88735068873506Falsely Elevated 25-Hydroxy-Vitamin D Levels in Patients with HypercalcemiaMoon Kyung Choi0Prapaipan Putthapiban1Patamaporn Lekprasert2Department of Internal Medicine, Einstein Medical Center Philadelphia, 5501 Old York Road, Philadelphia, PA 19141, USADepartment of Internal Medicine, Einstein Medical Center Philadelphia, 5501 Old York Road, Philadelphia, PA 19141, USADepartment of Endocrinology, Einstein Endocrine Associates, 50 East Township Line Road Medical Arts Building, Suite G01, Elkins Park, PA 19027, USASymptomatic hypercalcemia is a commonly encountered clinical scenario. Though it is important to collect detailed history to find clinical clues connecting to the etiology of hypercalcemia, the diagnostic workup of hypercalcemia depends heavily on laboratory analysis. Accurate measurement of the parathyroid hormone and vitamin D levels is essential. However, commercial laboratory measurement of vitamin D levels can be erroneous in the setting of abundant paraprotein in the serum. One of the most common conditions that can cause an increased amount of paraproteins is multiple myeloma. We report 2 cases of falsely elevated 25-hydroxy-vitamin D levels in patients presenting with hypercalcemia and an underlying diagnosis of MM.http://dx.doi.org/10.1155/2020/8873506 |
| spellingShingle | Moon Kyung Choi Prapaipan Putthapiban Patamaporn Lekprasert Falsely Elevated 25-Hydroxy-Vitamin D Levels in Patients with Hypercalcemia Case Reports in Endocrinology |
| title | Falsely Elevated 25-Hydroxy-Vitamin D Levels in Patients with Hypercalcemia |
| title_full | Falsely Elevated 25-Hydroxy-Vitamin D Levels in Patients with Hypercalcemia |
| title_fullStr | Falsely Elevated 25-Hydroxy-Vitamin D Levels in Patients with Hypercalcemia |
| title_full_unstemmed | Falsely Elevated 25-Hydroxy-Vitamin D Levels in Patients with Hypercalcemia |
| title_short | Falsely Elevated 25-Hydroxy-Vitamin D Levels in Patients with Hypercalcemia |
| title_sort | falsely elevated 25 hydroxy vitamin d levels in patients with hypercalcemia |
| url | http://dx.doi.org/10.1155/2020/8873506 |
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