Long Time from Diagnosis to Surgery May Increase Postoperative Complication Rates in Elective CD Intestinal Resections: An Observational Study
Background. There is lack of data analyzing short-term postoperative complications and time from diagnosis to surgery in Crohn’s disease (CD). Aim. To compare complication rates after elective abdominal operations in CD patients with different durations of disease. Methods. Retrospective observation...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2018/4703281 |
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| author | Paulo Gustavo Kotze Daniela Oliveira Magro Carlos Augusto Real Martinez Antonino Spinelli Takayuki Yamamoto Janindra Warusavitarne Claudio Saddy Rodrigues Coy |
| author_facet | Paulo Gustavo Kotze Daniela Oliveira Magro Carlos Augusto Real Martinez Antonino Spinelli Takayuki Yamamoto Janindra Warusavitarne Claudio Saddy Rodrigues Coy |
| author_sort | Paulo Gustavo Kotze |
| collection | DOAJ |
| description | Background. There is lack of data analyzing short-term postoperative complications and time from diagnosis to surgery in Crohn’s disease (CD). Aim. To compare complication rates after elective abdominal operations in CD patients with different durations of disease. Methods. Retrospective observational study with CD patients who submitted to elective intestinal resections. Patients were allocated in 2 groups according to time to surgery (TS) in less or more than 5 years. Short-term postoperative complications were analyzed and compared between the 2 groups, and binary logistic regression analysis was performed to check for significant variables. Results. 123 patients were finally included, 77 with TS > 5 years (62.6%) and 46 with TS < 5 years (37.4%). Patients with TS > 5 years had higher rates of overall surgical complications (p=0.011), reoperations (p=0.003), surgical site infections (p=0.014), anastomotic dehiscence (p=0.021), abdominal abscesses (p=0.021), and overall medical complications (p=0.019). On logistic regression, the single significant variable was the confection of stomas (OR: 3.203; 95% CI: 1.011–10.151; p=0.048). Conclusions. Patients with longer time to surgery showed a significant increase in overall medical and surgical postoperative early complications after elective intestinal resections. |
| format | Article |
| id | doaj-art-a1fcbf247f0441e38924e156ffe3efac |
| institution | OA Journals |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-a1fcbf247f0441e38924e156ffe3efac2025-08-20T02:20:42ZengWileyGastroenterology Research and Practice1687-61211687-630X2018-01-01201810.1155/2018/47032814703281Long Time from Diagnosis to Surgery May Increase Postoperative Complication Rates in Elective CD Intestinal Resections: An Observational StudyPaulo Gustavo Kotze0Daniela Oliveira Magro1Carlos Augusto Real Martinez2Antonino Spinelli3Takayuki Yamamoto4Janindra Warusavitarne5Claudio Saddy Rodrigues Coy6Colorectal Surgery Unit, Cajuru University Hospital, Pontifical Catholic University of Paraná (PUCPR), Curitiba, PR, BrazilColorectal Surgery Unit, University of Campinas (UNICAMP), Campinas, SP, BrazilColorectal Surgery Unit, University of Campinas (UNICAMP), Campinas, SP, BrazilDepartment of Colorectal Surgery, Humanitas Research Hospital, Rozzano, ItalyIBD Centre, Yokkaichi Hazu Medical Centre, Yokkaichi, JapanDepartment of Colorectal Surgery, St. Mark’s Hospital, Harrow, UKColorectal Surgery Unit, University of Campinas (UNICAMP), Campinas, SP, BrazilBackground. There is lack of data analyzing short-term postoperative complications and time from diagnosis to surgery in Crohn’s disease (CD). Aim. To compare complication rates after elective abdominal operations in CD patients with different durations of disease. Methods. Retrospective observational study with CD patients who submitted to elective intestinal resections. Patients were allocated in 2 groups according to time to surgery (TS) in less or more than 5 years. Short-term postoperative complications were analyzed and compared between the 2 groups, and binary logistic regression analysis was performed to check for significant variables. Results. 123 patients were finally included, 77 with TS > 5 years (62.6%) and 46 with TS < 5 years (37.4%). Patients with TS > 5 years had higher rates of overall surgical complications (p=0.011), reoperations (p=0.003), surgical site infections (p=0.014), anastomotic dehiscence (p=0.021), abdominal abscesses (p=0.021), and overall medical complications (p=0.019). On logistic regression, the single significant variable was the confection of stomas (OR: 3.203; 95% CI: 1.011–10.151; p=0.048). Conclusions. Patients with longer time to surgery showed a significant increase in overall medical and surgical postoperative early complications after elective intestinal resections.http://dx.doi.org/10.1155/2018/4703281 |
| spellingShingle | Paulo Gustavo Kotze Daniela Oliveira Magro Carlos Augusto Real Martinez Antonino Spinelli Takayuki Yamamoto Janindra Warusavitarne Claudio Saddy Rodrigues Coy Long Time from Diagnosis to Surgery May Increase Postoperative Complication Rates in Elective CD Intestinal Resections: An Observational Study Gastroenterology Research and Practice |
| title | Long Time from Diagnosis to Surgery May Increase Postoperative Complication Rates in Elective CD Intestinal Resections: An Observational Study |
| title_full | Long Time from Diagnosis to Surgery May Increase Postoperative Complication Rates in Elective CD Intestinal Resections: An Observational Study |
| title_fullStr | Long Time from Diagnosis to Surgery May Increase Postoperative Complication Rates in Elective CD Intestinal Resections: An Observational Study |
| title_full_unstemmed | Long Time from Diagnosis to Surgery May Increase Postoperative Complication Rates in Elective CD Intestinal Resections: An Observational Study |
| title_short | Long Time from Diagnosis to Surgery May Increase Postoperative Complication Rates in Elective CD Intestinal Resections: An Observational Study |
| title_sort | long time from diagnosis to surgery may increase postoperative complication rates in elective cd intestinal resections an observational study |
| url | http://dx.doi.org/10.1155/2018/4703281 |
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