Disruption of reproductive and thyroid endocrine systems in zebrafish following early life and whole life cycle exposure to low-dose norgestrel

Disruption of reproductive and thyroid endocrine systems in zebrafish following early life and whole life cycle exposure to low-dose norgestrel

Norgestrel (NGT), a synthetic progestin, is frequently detected in aquatic environments and known to disrupt fish endocrine systems. In this study, zebrafish embryos were exposed to low NGT concentrations (9 and 66 ng/L) for 90 days post-fertilization (dpf), covering embryonic-juvenile (0–30 dpf) an...

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Bibliographic Details
Main Authors: Shuyan Mai, Weicai Hu, Yan-Qiu Liang, Zhongdian Dong, Chang-Gui Pan, Zhiyun Liu, Runting Ouyang, Yangjie Zeng, Zhong Lin, Liping Hou
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Zebrafish
Norgestrel
Sex differentiation
Early life exposure
Whole life cycle exposure
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325012813
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