An Efficient CNN for Hand X-Ray Overall Scoring of Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a progressive systemic autoimmune disease characterized by inflammation of the joints and surrounding tissues, which seriously affects the life of patients. The Sharp/van der Heijde method has been widely used in clinical evaluation for the RA disease. However, this manu...

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Main Authors: Zijian Wang, Jian Liu, Zongyun Gu, Chuanfu Li
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Complexity
Online Access:http://dx.doi.org/10.1155/2022/5485606
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author Zijian Wang
Jian Liu
Zongyun Gu
Chuanfu Li
author_facet Zijian Wang
Jian Liu
Zongyun Gu
Chuanfu Li
author_sort Zijian Wang
collection DOAJ
description Rheumatoid arthritis (RA) is a progressive systemic autoimmune disease characterized by inflammation of the joints and surrounding tissues, which seriously affects the life of patients. The Sharp/van der Heijde method has been widely used in clinical evaluation for the RA disease. However, this manual method is time-consuming and laborious. Even if two radiologists evaluate a specific location, their subjective evaluation may lead to low inter-rater reliability. Here, we developed an efficient model powered by deep convolutional neural networks to solve these problems and automated the overall scoring on hand X-rays. The depthwise separable (Dwise) convolution technique is used based on ResNet-50 due to the high resolution of hand X-rays. An inverted residual block is introduced to devise a ResNet-Dwise50 model to enhance the efficiency of the model. The model was trained and tested using bilateral posteroanterior (two-handed, side by side) images of 3818 patients. The experiment results show the ResNet-Dwise50 model achieved an MAE of 14.90 and RMSE of 22.01 while ensuring high efficiency. There was no statistical difference between the average scores given by two experienced radiologists and predicted scores from our model.
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spelling doaj-art-a1dd71168bdd429ca5b139ccbe563ff82025-08-20T03:38:35ZengWileyComplexity1099-05262022-01-01202210.1155/2022/5485606An Efficient CNN for Hand X-Ray Overall Scoring of Rheumatoid ArthritisZijian Wang0Jian Liu1Zongyun Gu2Chuanfu Li3College of Medical Information EngineeringFirst Clinical Medical CollegeCollege of Medical Information EngineeringCollege of Medical Information EngineeringRheumatoid arthritis (RA) is a progressive systemic autoimmune disease characterized by inflammation of the joints and surrounding tissues, which seriously affects the life of patients. The Sharp/van der Heijde method has been widely used in clinical evaluation for the RA disease. However, this manual method is time-consuming and laborious. Even if two radiologists evaluate a specific location, their subjective evaluation may lead to low inter-rater reliability. Here, we developed an efficient model powered by deep convolutional neural networks to solve these problems and automated the overall scoring on hand X-rays. The depthwise separable (Dwise) convolution technique is used based on ResNet-50 due to the high resolution of hand X-rays. An inverted residual block is introduced to devise a ResNet-Dwise50 model to enhance the efficiency of the model. The model was trained and tested using bilateral posteroanterior (two-handed, side by side) images of 3818 patients. The experiment results show the ResNet-Dwise50 model achieved an MAE of 14.90 and RMSE of 22.01 while ensuring high efficiency. There was no statistical difference between the average scores given by two experienced radiologists and predicted scores from our model.http://dx.doi.org/10.1155/2022/5485606
spellingShingle Zijian Wang
Jian Liu
Zongyun Gu
Chuanfu Li
An Efficient CNN for Hand X-Ray Overall Scoring of Rheumatoid Arthritis
Complexity
title An Efficient CNN for Hand X-Ray Overall Scoring of Rheumatoid Arthritis
title_full An Efficient CNN for Hand X-Ray Overall Scoring of Rheumatoid Arthritis
title_fullStr An Efficient CNN for Hand X-Ray Overall Scoring of Rheumatoid Arthritis
title_full_unstemmed An Efficient CNN for Hand X-Ray Overall Scoring of Rheumatoid Arthritis
title_short An Efficient CNN for Hand X-Ray Overall Scoring of Rheumatoid Arthritis
title_sort efficient cnn for hand x ray overall scoring of rheumatoid arthritis
url http://dx.doi.org/10.1155/2022/5485606
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