A Lectin AtTL-2 Obtained from <i>Acropora</i> aff. <i>tenuis</i> Induced Stimualation of Phagocytosis of Symbiodiniaceae

The coral <i>Acropora</i> aff. <i>tenuis</i> selectively acquired various zooxanthella (Symbiodiniaceae) strains, and one of the selective factors was lectins. The <i>A</i>. aff. <i>tenuis</i> lectin AtTL-2 was identified as a factor for Symbiodiniacea...

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Main Authors: Mitsuru Jimbo, Nami Kuniya, Yuna Fujimaki, Daiki Yoshikawa, Naoki Kamiya, Haruna Amano, Ko Yasumoto, Ikuko Yuyama, Go Suzuki, Saki Harii
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Microorganisms
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Online Access:https://www.mdpi.com/2076-2607/13/5/1095
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Summary:The coral <i>Acropora</i> aff. <i>tenuis</i> selectively acquired various zooxanthella (Symbiodiniaceae) strains, and one of the selective factors was lectins. The <i>A</i>. aff. <i>tenuis</i> lectin AtTL-2 was identified as a factor for Symbiodiniaceae acquisition by the coral, but the mechanism is not fully known. The acquisition process involves three steps: chemotaxis, entry into the coral, and phagocytosis. In this study, we examined the function of AtTL-2 in more detail. Immunohistochemistry analysis was performed to examine the distribution of AtTL-2. The effect of AtTL-2 on the number of Symbiodiniaceae acquired was measured in <i>A.</i> aff. <i>tenuis</i> juvenile polyps with and without <i>AtTL-2</i> siRNA treatment. The effect of AtTL-2 fixation was examined by monitoring the acquisition of AtTL-2–fixed beads by <i>A.</i> aff. <i>tenuis</i>. AtTL-2 was distributed in nematocysts, spirocysts, and around Symbiodiniaceae. AtTL-2 siRNA inhibited the acquisition of Symbiodiniaceae by juvenile polyps. Fixation of AtTL-2 promoted bead acquisition by juvenile polyps more than fixation of bovine serum albumin (BSA). Moreover, more AtTL-2–fixed beads were bound to the Symbiodiniaceae-enclosed cells than BSA-fixed beads. AtTL-2 is released from spirocysts and binds to Symbiodiniaceae. AtTL-2 then promotes the phagocytosis of Symbiodiniaceae by gastrodermal cells of <i>A.</i> aff. <i>tenuis.</i>
ISSN:2076-2607