Glioblastoma. Past, present and future

<p>Glioblastoma is the most advanced, common and malignant stage of primary brain tumors in adults. It represents about 57% of all glial tumors. In adults it is more common in the cerebral hemispheres, while in children it is more common in the posterior fossa. Its infiltrative growth is extre...

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Main Authors: Adriel Herrero Díaz, Luis Manuel Abreu Pereira, Ilian Esteban Tarife Romero, Diana Rosa González Tamayo
Format: Article
Language:Spanish
Published: Centro Provincial de Información de Ciencias Médicas. Cienfuegos 2024-07-01
Series:Medisur
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Online Access:http://medisur.sld.cu/index.php/medisur/article/view/45195
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author Adriel Herrero Díaz
Luis Manuel Abreu Pereira
Ilian Esteban Tarife Romero
Diana Rosa González Tamayo
author_facet Adriel Herrero Díaz
Luis Manuel Abreu Pereira
Ilian Esteban Tarife Romero
Diana Rosa González Tamayo
author_sort Adriel Herrero Díaz
collection DOAJ
description <p>Glioblastoma is the most advanced, common and malignant stage of primary brain tumors in adults. It represents about 57% of all glial tumors. In adults it is more common in the cerebral hemispheres, while in children it is more common in the posterior fossa. Its infiltrative growth is extremely rapid. The present literature review aims to describe the clinical characteristics and treatment of glioblastoma as an aggressive brain tumor. A bibliographic search was carried out, resulting in 29 bibliographic sources, available in Scielo, PubMed, Dialnet and Elsevier, in which the information reviewed, was supported. Grade IV glioblastoma or astrocytoma is an aggressive, poorly differentiated tumor with a high degree of malignancy, invariably associated with a poor prognosis. Glioblastoma is positioned as the most aggressive form of brain cancer. Its treatment is based on tumor cytoreduction, combined with chemo and radiotherapy. The current numbers show unfavorable prognoses associated with this neoplasia. The improvement and creation of new anticancer therapies are the future hopes in the fight against this pathology.</p>
format Article
id doaj-art-a1d5418860f640728ec343e80d7cc3fb
institution Kabale University
issn 1727-897X
language Spanish
publishDate 2024-07-01
publisher Centro Provincial de Información de Ciencias Médicas. Cienfuegos
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series Medisur
spelling doaj-art-a1d5418860f640728ec343e80d7cc3fb2025-01-30T21:29:03ZspaCentro Provincial de Información de Ciencias Médicas. CienfuegosMedisur1727-897X2024-07-012248218272540Glioblastoma. Past, present and futureAdriel Herrero Díaz0Luis Manuel Abreu Pereira1Ilian Esteban Tarife Romero2Diana Rosa González Tamayo3Universidad de Ciencias Médicas de Villa Clara. Villa ClaraFacultad de Ciencias Médicas de Mayabeque. MayabequeFacultad de Ciencias Médicas de Mayabeque. MayabequeHospital Provincial Universitario Arnaldo Milián Castro. Villa Clara<p>Glioblastoma is the most advanced, common and malignant stage of primary brain tumors in adults. It represents about 57% of all glial tumors. In adults it is more common in the cerebral hemispheres, while in children it is more common in the posterior fossa. Its infiltrative growth is extremely rapid. The present literature review aims to describe the clinical characteristics and treatment of glioblastoma as an aggressive brain tumor. A bibliographic search was carried out, resulting in 29 bibliographic sources, available in Scielo, PubMed, Dialnet and Elsevier, in which the information reviewed, was supported. Grade IV glioblastoma or astrocytoma is an aggressive, poorly differentiated tumor with a high degree of malignancy, invariably associated with a poor prognosis. Glioblastoma is positioned as the most aggressive form of brain cancer. Its treatment is based on tumor cytoreduction, combined with chemo and radiotherapy. The current numbers show unfavorable prognoses associated with this neoplasia. The improvement and creation of new anticancer therapies are the future hopes in the fight against this pathology.</p>http://medisur.sld.cu/index.php/medisur/article/view/45195glioblastomanecrosisneoplasiasdiagnóstico
spellingShingle Adriel Herrero Díaz
Luis Manuel Abreu Pereira
Ilian Esteban Tarife Romero
Diana Rosa González Tamayo
Glioblastoma. Past, present and future
Medisur
glioblastoma
necrosis
neoplasias
diagnóstico
title Glioblastoma. Past, present and future
title_full Glioblastoma. Past, present and future
title_fullStr Glioblastoma. Past, present and future
title_full_unstemmed Glioblastoma. Past, present and future
title_short Glioblastoma. Past, present and future
title_sort glioblastoma past present and future
topic glioblastoma
necrosis
neoplasias
diagnóstico
url http://medisur.sld.cu/index.php/medisur/article/view/45195
work_keys_str_mv AT adrielherrerodiaz glioblastomapastpresentandfuture
AT luismanuelabreupereira glioblastomapastpresentandfuture
AT ilianestebantariferomero glioblastomapastpresentandfuture
AT dianarosagonzaleztamayo glioblastomapastpresentandfuture