TOMM40 may mediate GFAP, neurofilament light Protein, pTau181, and brain morphometry in aging

TOMM40 may mediate GFAP, neurofilament light Protein, pTau181, and brain morphometry in aging

A growing amount of data has implicated the TOMM40 gene in the risk for Alzheimer’s disease (AD), neurodegeneration, and accelerated aging. No studies have investigated the relationship of TOMM40 rs2075650 (‘650) on the structural complexity of the brain or plasma markers of neurodegeneration. We us...

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Bibliographic Details
Main Authors: Robyn A. Honea, Heather Wilkins, Suzanne L. Hunt, Paul J. Kueck, Jeffrey M. Burns, Russell H. Swerdlow, Jill K. Morris
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Aging Brain
Subjects:
TOMM40
APOE
NfL
pTau181
Aging
GFAP
Online Access:http://www.sciencedirect.com/science/article/pii/S2589958924000306
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