Rescue Fibrinolysis in STEMI Patients with Failed Primary Percutaneous Coronary Intervention at Hanoi Medical University Hospital
<b>Background</b>: ST-elevation myocardial infarction (STEMI) is a life-threatening emergency. Primary percutaneous coronary intervention (PPCI) is the preferred reperfusion strategy, provided it is performed promptly (within 120 min of the ECG-based diagnosis). However, the failure rate...
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MDPI AG
2025-03-01
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| Series: | Emergency Care and Medicine |
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| Online Access: | https://www.mdpi.com/2813-7914/2/2/17 |
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| author | Bui Hai Hoang Dinh Hung Vu Michael M. Dinh Nguyen Dai Nghia Phan Thi Huong Thao Bui Giang Phuc Do Lan Hieu Nguyen |
| author_facet | Bui Hai Hoang Dinh Hung Vu Michael M. Dinh Nguyen Dai Nghia Phan Thi Huong Thao Bui Giang Phuc Do Lan Hieu Nguyen |
| author_sort | Bui Hai Hoang |
| collection | DOAJ |
| description | <b>Background</b>: ST-elevation myocardial infarction (STEMI) is a life-threatening emergency. Primary percutaneous coronary intervention (PPCI) is the preferred reperfusion strategy, provided it is performed promptly (within 120 min of the ECG-based diagnosis). However, the failure rate of PPCI remains high, particularly in patients with more severe conditions, potentially leading to serious complications. <b>Objective:</b> Through this case, we want to introduce coronary fibrinolysis as a rescue therapy after failing with primary PPCI. <b>Methods:</b> Case report. <b>Results:</b> We reported a clinical case of a STEMI patient who underwent coronary fibrinolysis as a rescue therapy after PPCI failure. The patient was a 62-year-old male patient who was a 40-pack-year smoker. He was diagnosed with STEMI and immediately received PPCI, but the aspiration process and angioplasty were unsuccessful. Subsequently, we decided to use coronary fibrinolysis and the follow-up coronary angiography showed coronary revascularization, and chest pain was resolved. <b>Conclusions</b>: This case highlighted a potential therapeutic approach of coronary fibrinolysis for patients experiencing PPCI failure. |
| format | Article |
| id | doaj-art-a1cd1b3e4fc34957933ba6f8f4d53b4f |
| institution | OA Journals |
| issn | 2813-7914 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Emergency Care and Medicine |
| spelling | doaj-art-a1cd1b3e4fc34957933ba6f8f4d53b4f2025-08-20T02:24:21ZengMDPI AGEmergency Care and Medicine2813-79142025-03-01221710.3390/ecm2020017Rescue Fibrinolysis in STEMI Patients with Failed Primary Percutaneous Coronary Intervention at Hanoi Medical University HospitalBui Hai Hoang0Dinh Hung Vu1Michael M. Dinh2Nguyen Dai Nghia Phan3Thi Huong Thao Bui4Giang Phuc Do5Lan Hieu Nguyen6Emergency and Critical Care Department, Hanoi Medical University Hospital, Hanoi 100000, VietnamEmergency and Critical Care Department, Hanoi Medical University Hospital, Hanoi 100000, VietnamSydney Medical School, The University of Sydney, Sydney, NSW 2050, AustraliaEmergency and Critical Care Department, Hanoi Medical University Hospital, Hanoi 100000, VietnamPharmacology Department, Hanoi Medical University, Hanoi 100000, VietnamEmergency and Critical Care Department, Hanoi Medical University Hospital, Hanoi 100000, VietnamCardiology Center, Hanoi Medical University Hospital, Hanoi 100000, Vietnam<b>Background</b>: ST-elevation myocardial infarction (STEMI) is a life-threatening emergency. Primary percutaneous coronary intervention (PPCI) is the preferred reperfusion strategy, provided it is performed promptly (within 120 min of the ECG-based diagnosis). However, the failure rate of PPCI remains high, particularly in patients with more severe conditions, potentially leading to serious complications. <b>Objective:</b> Through this case, we want to introduce coronary fibrinolysis as a rescue therapy after failing with primary PPCI. <b>Methods:</b> Case report. <b>Results:</b> We reported a clinical case of a STEMI patient who underwent coronary fibrinolysis as a rescue therapy after PPCI failure. The patient was a 62-year-old male patient who was a 40-pack-year smoker. He was diagnosed with STEMI and immediately received PPCI, but the aspiration process and angioplasty were unsuccessful. Subsequently, we decided to use coronary fibrinolysis and the follow-up coronary angiography showed coronary revascularization, and chest pain was resolved. <b>Conclusions</b>: This case highlighted a potential therapeutic approach of coronary fibrinolysis for patients experiencing PPCI failure.https://www.mdpi.com/2813-7914/2/2/17acute myocardial infarction (AMI)primary percutaneous coronary intervention (PPCI)coronary systemic fibrinolysis |
| spellingShingle | Bui Hai Hoang Dinh Hung Vu Michael M. Dinh Nguyen Dai Nghia Phan Thi Huong Thao Bui Giang Phuc Do Lan Hieu Nguyen Rescue Fibrinolysis in STEMI Patients with Failed Primary Percutaneous Coronary Intervention at Hanoi Medical University Hospital Emergency Care and Medicine acute myocardial infarction (AMI) primary percutaneous coronary intervention (PPCI) coronary systemic fibrinolysis |
| title | Rescue Fibrinolysis in STEMI Patients with Failed Primary Percutaneous Coronary Intervention at Hanoi Medical University Hospital |
| title_full | Rescue Fibrinolysis in STEMI Patients with Failed Primary Percutaneous Coronary Intervention at Hanoi Medical University Hospital |
| title_fullStr | Rescue Fibrinolysis in STEMI Patients with Failed Primary Percutaneous Coronary Intervention at Hanoi Medical University Hospital |
| title_full_unstemmed | Rescue Fibrinolysis in STEMI Patients with Failed Primary Percutaneous Coronary Intervention at Hanoi Medical University Hospital |
| title_short | Rescue Fibrinolysis in STEMI Patients with Failed Primary Percutaneous Coronary Intervention at Hanoi Medical University Hospital |
| title_sort | rescue fibrinolysis in stemi patients with failed primary percutaneous coronary intervention at hanoi medical university hospital |
| topic | acute myocardial infarction (AMI) primary percutaneous coronary intervention (PPCI) coronary systemic fibrinolysis |
| url | https://www.mdpi.com/2813-7914/2/2/17 |
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