Genetic engineering of hematopoiesis: current stage of clinical translation and future perspectives
Abstract Here I review the scientific background, current stage of development and future perspectives that I foresee in the field of genetic manipulation of hematopoietic stem cells with a special emphasis on clinical applications.
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| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2019-01-01
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| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/emmm.201809958 |
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| _version_ | 1849342856650555392 |
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| author | Luigi Naldini |
| author_facet | Luigi Naldini |
| author_sort | Luigi Naldini |
| collection | DOAJ |
| description | Abstract Here I review the scientific background, current stage of development and future perspectives that I foresee in the field of genetic manipulation of hematopoietic stem cells with a special emphasis on clinical applications. |
| format | Article |
| id | doaj-art-a1cab8539bed46658774aadd2eff155b |
| institution | Kabale University |
| issn | 1757-4676 1757-4684 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Springer Nature |
| record_format | Article |
| series | EMBO Molecular Medicine |
| spelling | doaj-art-a1cab8539bed46658774aadd2eff155b2025-08-20T03:43:14ZengSpringer NatureEMBO Molecular Medicine1757-46761757-46842019-01-0111311210.15252/emmm.201809958Genetic engineering of hematopoiesis: current stage of clinical translation and future perspectivesLuigi Naldini0San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Hospital and Research Institute, “Vita ‐ Salute San Raffaele” University Medical SchoolAbstract Here I review the scientific background, current stage of development and future perspectives that I foresee in the field of genetic manipulation of hematopoietic stem cells with a special emphasis on clinical applications.https://doi.org/10.15252/emmm.201809958gene editinggene therapyhematopoietic stem cellslentiviral vectorstransplantation |
| spellingShingle | Luigi Naldini Genetic engineering of hematopoiesis: current stage of clinical translation and future perspectives EMBO Molecular Medicine gene editing gene therapy hematopoietic stem cells lentiviral vectors transplantation |
| title | Genetic engineering of hematopoiesis: current stage of clinical translation and future perspectives |
| title_full | Genetic engineering of hematopoiesis: current stage of clinical translation and future perspectives |
| title_fullStr | Genetic engineering of hematopoiesis: current stage of clinical translation and future perspectives |
| title_full_unstemmed | Genetic engineering of hematopoiesis: current stage of clinical translation and future perspectives |
| title_short | Genetic engineering of hematopoiesis: current stage of clinical translation and future perspectives |
| title_sort | genetic engineering of hematopoiesis current stage of clinical translation and future perspectives |
| topic | gene editing gene therapy hematopoietic stem cells lentiviral vectors transplantation |
| url | https://doi.org/10.15252/emmm.201809958 |
| work_keys_str_mv | AT luiginaldini geneticengineeringofhematopoiesiscurrentstageofclinicaltranslationandfutureperspectives |