The importance of serum levels and genetic characteristics of anti-inflammatory cytokines in patients with atopic dermatitis
The article presents the results of the IL-4, IL-10 and IL-13 serum level study in patients with atopic dermatitis and evaluation of the ratio between the obtained values and the occurrence of the genotypes of the selected polymorphisms in the encoding genes. The results showed higher concentrations...
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| Format: | Article |
| Language: | Russian |
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Open Systems Publication
2021-06-01
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| Series: | Лечащий Врач |
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| Online Access: | https://journal.lvrach.ru/jour/article/view/667 |
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| _version_ | 1849744322692382720 |
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| author | I. V. Kosheleva A. R. Khasanova I. S. Belyakov |
| author_facet | I. V. Kosheleva A. R. Khasanova I. S. Belyakov |
| author_sort | I. V. Kosheleva |
| collection | DOAJ |
| description | The article presents the results of the IL-4, IL-10 and IL-13 serum level study in patients with atopic dermatitis and evaluation of the ratio between the obtained values and the occurrence of the genotypes of the selected polymorphisms in the encoding genes. The results showed higher concentrations of IL-10 and IL-13 in patients with atopic dermatitis. There were no significant changes in serum levels of IL-4 in patients with atopic dermatitis and healthy volunteers. |
| format | Article |
| id | doaj-art-a1c9d568379348cc917ddfd4d8f1ddca |
| institution | DOAJ |
| issn | 1560-5175 2687-1181 |
| language | Russian |
| publishDate | 2021-06-01 |
| publisher | Open Systems Publication |
| record_format | Article |
| series | Лечащий Врач |
| spelling | doaj-art-a1c9d568379348cc917ddfd4d8f1ddca2025-08-20T03:20:17ZrusOpen Systems PublicationЛечащий Врач1560-51752687-11812021-06-0101666The importance of serum levels and genetic characteristics of anti-inflammatory cytokines in patients with atopic dermatitisI. V. Kosheleva0A. R. Khasanova1I. S. Belyakov2ФГБОУ ДПО РМАНПО МЗ РФФГБОУ ДПО РМАНПО МЗ РФФГБОУ ДПО РМАНПО МЗ РФThe article presents the results of the IL-4, IL-10 and IL-13 serum level study in patients with atopic dermatitis and evaluation of the ratio between the obtained values and the occurrence of the genotypes of the selected polymorphisms in the encoding genes. The results showed higher concentrations of IL-10 and IL-13 in patients with atopic dermatitis. There were no significant changes in serum levels of IL-4 in patients with atopic dermatitis and healthy volunteers.https://journal.lvrach.ru/jour/article/view/667atopic dermatitisinterleukinscytokinesgenegenotypepolymorphism |
| spellingShingle | I. V. Kosheleva A. R. Khasanova I. S. Belyakov The importance of serum levels and genetic characteristics of anti-inflammatory cytokines in patients with atopic dermatitis Лечащий Врач atopic dermatitis interleukins cytokines gene genotype polymorphism |
| title | The importance of serum levels and genetic characteristics of anti-inflammatory cytokines in patients with atopic dermatitis |
| title_full | The importance of serum levels and genetic characteristics of anti-inflammatory cytokines in patients with atopic dermatitis |
| title_fullStr | The importance of serum levels and genetic characteristics of anti-inflammatory cytokines in patients with atopic dermatitis |
| title_full_unstemmed | The importance of serum levels and genetic characteristics of anti-inflammatory cytokines in patients with atopic dermatitis |
| title_short | The importance of serum levels and genetic characteristics of anti-inflammatory cytokines in patients with atopic dermatitis |
| title_sort | importance of serum levels and genetic characteristics of anti inflammatory cytokines in patients with atopic dermatitis |
| topic | atopic dermatitis interleukins cytokines gene genotype polymorphism |
| url | https://journal.lvrach.ru/jour/article/view/667 |
| work_keys_str_mv | AT ivkosheleva theimportanceofserumlevelsandgeneticcharacteristicsofantiinflammatorycytokinesinpatientswithatopicdermatitis AT arkhasanova theimportanceofserumlevelsandgeneticcharacteristicsofantiinflammatorycytokinesinpatientswithatopicdermatitis AT isbelyakov theimportanceofserumlevelsandgeneticcharacteristicsofantiinflammatorycytokinesinpatientswithatopicdermatitis AT ivkosheleva importanceofserumlevelsandgeneticcharacteristicsofantiinflammatorycytokinesinpatientswithatopicdermatitis AT arkhasanova importanceofserumlevelsandgeneticcharacteristicsofantiinflammatorycytokinesinpatientswithatopicdermatitis AT isbelyakov importanceofserumlevelsandgeneticcharacteristicsofantiinflammatorycytokinesinpatientswithatopicdermatitis |