Toxicity of Ulva lactuca and green fabricated silver nanoparticles against mosquito vectors and their impact on the genomic DNA of the dengue vector Aedes aegypti
Abstract Marine seaweeds are known to have a potential role against microbial and pesticidal activities. Ulva lactuca, a green macroalgae extract analysed through gas chromatography mass spectrometry reveals 31 compounds. Resistance of mosquito vectors to synthetic insecticides remains a major probl...
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Wiley
2022-06-01
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| Series: | IET Nanobiotechnology |
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| Online Access: | https://doi.org/10.1049/nbt2.12082 |
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| author | Al Thabiani Aziz |
| author_facet | Al Thabiani Aziz |
| author_sort | Al Thabiani Aziz |
| collection | DOAJ |
| description | Abstract Marine seaweeds are known to have a potential role against microbial and pesticidal activities. Ulva lactuca, a green macroalgae extract analysed through gas chromatography mass spectrometry reveals 31 compounds. Resistance of mosquito vectors to synthetic insecticides remains a major problem. Discovering and applying natural agents to act against disease vectors is challenging. The activities of the extract and nano‐fabricated green synthesised silver nanoparticles were checked for use against Aedes aegypti and Culex pipiens. The crude extract and synthesised silver nanoparticles exhibited a notable larvicidal effect, and very effective inhibition of pupal and adult emergence. Inhibition of adult emergence of Ae.aegypti was 97.7% and in Cu.pipiens, it was 93.3%. Our genotypic study of Deoxyribonucleic acid from treated larvae utilising random primers MA‐09, MA‐12 and MA‐26 revealed damaged nucleotide sequences when compared with the controls. The antimicrobial activity of both the extract and green synthesised nanomaterials showed prominent activity against pathogenic drug resistant bacteria. Our results contribute to further development of eco‐friendly insecticides with lower cost of preparation. This could further contribute to further research helping future generations to be free from these deadly disease‐causing vectors and pathogenic microbes. |
| format | Article |
| id | doaj-art-a1bbd5a9b0b84899b9499122521265a4 |
| institution | Kabale University |
| issn | 1751-8741 1751-875X |
| language | English |
| publishDate | 2022-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | IET Nanobiotechnology |
| spelling | doaj-art-a1bbd5a9b0b84899b9499122521265a42025-02-03T01:31:56ZengWileyIET Nanobiotechnology1751-87411751-875X2022-06-0116414515710.1049/nbt2.12082Toxicity of Ulva lactuca and green fabricated silver nanoparticles against mosquito vectors and their impact on the genomic DNA of the dengue vector Aedes aegyptiAl Thabiani Aziz0Department of Biology Faculty of Science University of Tabuk Tabuk Saudi ArabiaAbstract Marine seaweeds are known to have a potential role against microbial and pesticidal activities. Ulva lactuca, a green macroalgae extract analysed through gas chromatography mass spectrometry reveals 31 compounds. Resistance of mosquito vectors to synthetic insecticides remains a major problem. Discovering and applying natural agents to act against disease vectors is challenging. The activities of the extract and nano‐fabricated green synthesised silver nanoparticles were checked for use against Aedes aegypti and Culex pipiens. The crude extract and synthesised silver nanoparticles exhibited a notable larvicidal effect, and very effective inhibition of pupal and adult emergence. Inhibition of adult emergence of Ae.aegypti was 97.7% and in Cu.pipiens, it was 93.3%. Our genotypic study of Deoxyribonucleic acid from treated larvae utilising random primers MA‐09, MA‐12 and MA‐26 revealed damaged nucleotide sequences when compared with the controls. The antimicrobial activity of both the extract and green synthesised nanomaterials showed prominent activity against pathogenic drug resistant bacteria. Our results contribute to further development of eco‐friendly insecticides with lower cost of preparation. This could further contribute to further research helping future generations to be free from these deadly disease‐causing vectors and pathogenic microbes.https://doi.org/10.1049/nbt2.12082Aedes aegyptiantimicrobialCulex pipiensRAPDvectors |
| spellingShingle | Al Thabiani Aziz Toxicity of Ulva lactuca and green fabricated silver nanoparticles against mosquito vectors and their impact on the genomic DNA of the dengue vector Aedes aegypti IET Nanobiotechnology Aedes aegypti antimicrobial Culex pipiens RAPD vectors |
| title | Toxicity of Ulva lactuca and green fabricated silver nanoparticles against mosquito vectors and their impact on the genomic DNA of the dengue vector Aedes aegypti |
| title_full | Toxicity of Ulva lactuca and green fabricated silver nanoparticles against mosquito vectors and their impact on the genomic DNA of the dengue vector Aedes aegypti |
| title_fullStr | Toxicity of Ulva lactuca and green fabricated silver nanoparticles against mosquito vectors and their impact on the genomic DNA of the dengue vector Aedes aegypti |
| title_full_unstemmed | Toxicity of Ulva lactuca and green fabricated silver nanoparticles against mosquito vectors and their impact on the genomic DNA of the dengue vector Aedes aegypti |
| title_short | Toxicity of Ulva lactuca and green fabricated silver nanoparticles against mosquito vectors and their impact on the genomic DNA of the dengue vector Aedes aegypti |
| title_sort | toxicity of ulva lactuca and green fabricated silver nanoparticles against mosquito vectors and their impact on the genomic dna of the dengue vector aedes aegypti |
| topic | Aedes aegypti antimicrobial Culex pipiens RAPD vectors |
| url | https://doi.org/10.1049/nbt2.12082 |
| work_keys_str_mv | AT althabianiaziz toxicityofulvalactucaandgreenfabricatedsilvernanoparticlesagainstmosquitovectorsandtheirimpactonthegenomicdnaofthedenguevectoraedesaegypti |