The Human Microbiome: An Invisible Key to Unlocking Wellness
Bacteria that are important for nutrition and health predominantly live in a healthy gut. Gut dysbiosis results from alterations in gut homeostasis. Contemporary probiotics are used to treat gastrointestinal (GI) problems. Probiotic-producing genera include Lactobacillus, Clostridium, Bifidobacteriu...
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| Format: | Article |
| Language: | English |
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Journal of Pure and Applied Microbiology
2025-03-01
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| Series: | Journal of Pure and Applied Microbiology |
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| Online Access: | https://microbiologyjournal.org/the-human-microbiome-an-invisible-key-to-unlocking-wellness/ |
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| author | Kunal Mansi Dubey Sangeeta Kumari Machiavelli Singh |
| author_facet | Kunal Mansi Dubey Sangeeta Kumari Machiavelli Singh |
| author_sort | Kunal |
| collection | DOAJ |
| description | Bacteria that are important for nutrition and health predominantly live in a healthy gut. Gut dysbiosis results from alterations in gut homeostasis. Contemporary probiotics are used to treat gastrointestinal (GI) problems. Probiotic-producing genera include Lactobacillus, Clostridium, Bifidobacterium, and Streptococcus, which account for many probiotic strains currently in use. Recent improvements in culturomics, using new methods combined with gnotobiotic animal models, offer a solid foundation for the development of innovative host-specific probiotic treatments. The GI tract begins from the mouth and ends at the anus, and it controls food consumption and digestion. Along with aiding food digestion, the GI tract acts as an immune system and a physical barrier against potentially hazardous germs, foreign objects, and antigens. The principal location of nutritional absorption is the gut, which includes the stomach and the small and large intestines. Contemporary probiotics contain well-characterized live microbes that can manipulate the gut and provide health benefits. Based on the available literature, the normal gut microbiota can be restored to preserve gut integrity and host health. Changes or dysfunctions in the microbiome can lead to various illnesses, such as inflammatory bowel disease, obesity, and autoimmune disorders. Prebiotics, probiotics, and fecal microbiota transplantation are only a few of the treatment strategies discussed in this article, along with their advantages, drawbacks, and potential future research areas. Furthermore, it highlights the current studies linking the gut microbiota to COVID-19 and their potential implications for disease treatment and prevention. A topic on the future of microbiome research and how it will enhance general wellness is presented in the article’s conclusion. |
| format | Article |
| id | doaj-art-a1bb98bed413449c8a406f5787dddb61 |
| institution | Kabale University |
| issn | 0973-7510 2581-690X |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Journal of Pure and Applied Microbiology |
| record_format | Article |
| series | Journal of Pure and Applied Microbiology |
| spelling | doaj-art-a1bb98bed413449c8a406f5787dddb612025-08-20T03:42:35ZengJournal of Pure and Applied MicrobiologyJournal of Pure and Applied Microbiology0973-75102581-690X2025-03-011914963https://doi.org/10.22207/JPAM.19.1.20The Human Microbiome: An Invisible Key to Unlocking WellnessKunalhttps://orcid.org/0000-0002-7482-7735Mansi DubeySangeeta Kumarihttps://orcid.org/0000-0001-8528-8776Machiavelli Singhhttps://orcid.org/0000-0001-7472-4587Bacteria that are important for nutrition and health predominantly live in a healthy gut. Gut dysbiosis results from alterations in gut homeostasis. Contemporary probiotics are used to treat gastrointestinal (GI) problems. Probiotic-producing genera include Lactobacillus, Clostridium, Bifidobacterium, and Streptococcus, which account for many probiotic strains currently in use. Recent improvements in culturomics, using new methods combined with gnotobiotic animal models, offer a solid foundation for the development of innovative host-specific probiotic treatments. The GI tract begins from the mouth and ends at the anus, and it controls food consumption and digestion. Along with aiding food digestion, the GI tract acts as an immune system and a physical barrier against potentially hazardous germs, foreign objects, and antigens. The principal location of nutritional absorption is the gut, which includes the stomach and the small and large intestines. Contemporary probiotics contain well-characterized live microbes that can manipulate the gut and provide health benefits. Based on the available literature, the normal gut microbiota can be restored to preserve gut integrity and host health. Changes or dysfunctions in the microbiome can lead to various illnesses, such as inflammatory bowel disease, obesity, and autoimmune disorders. Prebiotics, probiotics, and fecal microbiota transplantation are only a few of the treatment strategies discussed in this article, along with their advantages, drawbacks, and potential future research areas. Furthermore, it highlights the current studies linking the gut microbiota to COVID-19 and their potential implications for disease treatment and prevention. A topic on the future of microbiome research and how it will enhance general wellness is presented in the article’s conclusion.https://microbiologyjournal.org/the-human-microbiome-an-invisible-key-to-unlocking-wellness/covid-19gut-brain axisgut-skin axisoral microbiotatherapeutic interventions |
| spellingShingle | Kunal Mansi Dubey Sangeeta Kumari Machiavelli Singh The Human Microbiome: An Invisible Key to Unlocking Wellness Journal of Pure and Applied Microbiology covid-19 gut-brain axis gut-skin axis oral microbiota therapeutic interventions |
| title | The Human Microbiome: An Invisible Key to Unlocking Wellness |
| title_full | The Human Microbiome: An Invisible Key to Unlocking Wellness |
| title_fullStr | The Human Microbiome: An Invisible Key to Unlocking Wellness |
| title_full_unstemmed | The Human Microbiome: An Invisible Key to Unlocking Wellness |
| title_short | The Human Microbiome: An Invisible Key to Unlocking Wellness |
| title_sort | human microbiome an invisible key to unlocking wellness |
| topic | covid-19 gut-brain axis gut-skin axis oral microbiota therapeutic interventions |
| url | https://microbiologyjournal.org/the-human-microbiome-an-invisible-key-to-unlocking-wellness/ |
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